Rosemary Dziak

Rosemary Dziak

Rosemary Dziak

Contact Information
Foster Hall
Room 318
3435 Main Street
Buffalo, NY 14214
Phone: (716) 829-3827
Fax: (716) 829-3942
rdziak@buffalo.edu



Education and Training:

  • Postdoctoral Fellow, Pharmacology, Northwestern U. Medical School, NIH Postdoctoral Fellow (1975)
  • PhD, Radiation Biology, University of Rochester (1973)
  • MS, Radiation Biology, University of Rochester (1969)
  • BS, Biology, College Misericordia, magna cum laude (1967)

Employment:

  • Professor, Oral Biology, SUNY at Buffalo (1989-present)
  • Co-Director, Institute for Research and Education on Women and Gender, University at Buffalo (2005–2011)
  • Director-DDS/Ph.D. combined training Program Director, Oral Biology, SUNY at Buffalo (1996–2006)
  • Interim Chair, Oral Biology, SUNY at Buffalo (2002–2004)
  • Associate Chairman, Oral Biology, Oral Biology (1994–2000)
  • Director-Ph.D. Graduate Program in Oral Biology, Oral Biology, SUNY at Buffalo (1979–1999)
  • Associate Professor, Oral Biology, SUNY at Buffalo (1983–1989)
  • Acting Associate Chairperson, Oral Biology, SUNY at Buffalo (1987)
  • Assistant Professor-Dept.of Oral Biology, Oral Biology, SUNY at Buffalo (1977–1983)
  • Assistant Research Professor-Dept.of Oral Biology, Oral Biology, SUNY at Buffalo (1976)
  • Instructor, Physiology Department, Louisiana State University (1975–1976)
  • Instructor-Biology Department, College Misericordia (1969–1970)
See all (2 more)

Awards and Honors:

  • Award for Mentoring Dental Student Research (2015)
  • Charles S. Lipani Award for Service to UB School of Dental Medicine (2014)
  • Promising Inventor Award (2002)
  • NIH Research Career Development Award (1985)
  • NIH Research Career Development Award (1984)
  • Award for Contribution to Dental Student Research (1984)
  • NIH Research Career Development Award (1983)
  • NIH Research Career Development Award (1982)
  • NIH Research Career Development Award (1981)
  • NIH Research Career Development Award (1980)
  • George S. Clark Memorial Fund Research Fellow of Arthritis Foundation (1976)
  • NIH Special Fellowship (1975)
  • NIH Special Fellowship (1974)
  • NDEA Title IV (1973)
  • NDEA Title IV (1972)
  • NDEA Title IV (1971)
  • NDEA Title IV (1970)
  • AEC Special Health Physics (1969)
  • AEC Special Health Physics (1968)
  • AEC Special Health Physics (1967)
  • American Men and Women in Science
  • Who's Who in the East

Research Expertise:

  • Bone Cell Physiologist: Isolation and culturing of human osteoblastic cells; signal transduction maechanisms related to proliferation and differentiation of bone cells; tissue engineering; design of new materials for bone regeneration

Grants and Sponsored Research:

  • April 2017–March 2018
    Modification of healing abutment surface with strontium containing alginate gel to promote gingival fibroblast function
    International Congress of Oral Implantalogists
    Role: Co-Investigator
    $24,968
  • January 2017–December 2017
    Strontium and Mucosal Attachment to Healing Abutment Surfaces
    American academy of Implant Dentistry
    Role: Principal Investigator
    $7,300
  • February 2013–January 2014
    Nanocalcium sulfate as a bone regenerative agent
    Bruce Holm Memorial Catalyst Fund
    Role: Principal Investigator
    $50,000
  • October 2008–September 2009
    Improved Tissue Regenerative Device for the Oral Cavity
    Therex
    Role: Principal Investigator
    $39,000
  • February 2007–March 2008
    Growth Factor Delivery System with Nano-particles of Calcium Sulfate to Enhance Vertical Bone Augmentation with Dental Implant in a Canine Model
    Osseointegration Society
    Role: Co-Investigator
    $15,000
  • January 1999–December 2005
    Bone Regeneration Studies with PDGF
    Biomimetics, Inc.
    Role: Principal Investigator
    $75,000
  • November 2004–October 2005
    Effects of Emdogain on Cytokine Production.
    Institut Straumann AG, Waldenburg, Switzerland
    Role: Principal Investigator
    $5,000
  • March 2002–December 2003
    Regeneration with PDGF on Osteoconductive Materials
    Biomimetics, Inc.
    Role: Principal Investigator
    $75,300
  • January 2002–December 2003
    Regeneration with PDGF-Treated Osteoconductive Materials
    National Institute of Dental Research
    Role: Co-Principal Investigator
    $135,329
  • January 1996–December 2002
    D.D.S./Ph.D. Combined Training Program
    NIH
    Role: Principal Investigator
    $844,875
  • July 1996–July 2001
    DDS/PhD Combined Training Program
    NIDCR
    Role: Principal Investigator
    $844,875
  • September 1996–June 2001
    D.D.S./Ph.D. Combined Training Program.
    NIDR
    Role: Principal Investigator
    $81,864
  • December 1997–November 1999
    Enchantment of the Osteogenic Properties of Hydroxyapatitic Materials with Growth Factor
    Proctor & Gamble
    Role: Principal Investigator
    $5,000
  • October 1996–September 1997
    In vitro Studies with BioOss
    Osteohealth Corporation
    Role: Principal Investigator
    $25,000
  • September 1994–September 1997
    Research Program in Biological Sciences for Minorities
    NIH
    Role: Principal Investigator
    $87,712
  • April 1991–March 1996
    Bone Cell Calcium Regulation Renewal 4
    NIH
    Role: Principal Investigator
    $365,384
  • June 1989–August 1994
    Young Scholars Program in Biological Sciences
    NSF
    Role: Principal Investigator
    $106,000
  • April 1988–March 1991
    Bone Cell Calcium Regulation Renewal 3
    NIH
    Role: Principal Investigator
    $121,429
  • January 1989–November 1989
    Interleukin-1 Effects on Plasminogen Activator Levels in Osteoblastic Cells
    Arthritis Foundation of W.N.Y.
    Role: Principal Investigator
    $5,500
  • January 1988–December 1988
    Role of Leukotrienes in Interleukin-1 Effects on Bone Resorption
    Arthritis Foundation of W.N.Y.
    Role: Principal Investigator
    $5,500
  • January 1985–December 1987
    Role of Calcium in the Regulation of Bone Cell Prostaglandin Synthesis
    Arthritis Foundation W.N.Y.
    Role: Principal Investigator
    $12,000
  • January 1985–December 1986
    Evaluation of Bioresorbable Materials in Contact with Bone
    Davis & Geck
    Role: Principal Investigator
    $30,000
  • April 1983–March 1986
    Bone Cell Calcium Regulation Renewal 2
    NIH
    Role: Principal Investigator
    $86,515
  • April 1980–March 1985
    Research Career Development Award
    N.I.H.
    Role: Principal Investigator
  • April 1980–March 1983
    Bone Cell Calcium Regulation Renewal 1
    National Institute of Dental Research (SDRA)
    Role: Principal Investigator
    $61,299
  • April 1981–March 1982
    Regulation of Prostaglandin Binding in Bone
    The Arthritis Foundation (Western N.Y.)
    Role: Principal Investigator
    $10,000
  • January 1980–December 1980
    Prostaglandin Studies in Bone
    The Arthritis Foundation (Western N.Y.)
    Role: Principal Investigator
    $6,000
  • June 1976–May 1979
    Bone Cell Calcium Regulation
    National Institute of Dental Research (SDRA)
    Role: Co-Investigator
    $54,322
  • January 1975–December 1976
    Corticosteroids Effects on Bone Cell Calcium
    Louisiana Chapter, The Arthritis Foundation
    Role: Principal Investigator
    $3,000
See all (19 more)

Patents:

  • Tissue Engineering of an Efficient Bone Graft Material Provisional patent (2008)
  • Nano-Particles of Calcium Sulfate as a Growth Factor Delivery System (2007)

Journal Articles:

  • Andrew W. Barone, Gabriela Fernandes, Rosemary Dziak. Effects of alendronate and interferon-γ on bone cancer cells in vitro. Cogent Biology. 2018; 4(1).
  • Rosemary Dziak, Dalia Nourah, That AlHousami, Dinh Nguyen. Effects of Chromeceptin on Insulin-like Growth Factor II in Human Osteoblastic and Osteosarcoma CellsJou. Journal of Bone Biology and Osteoporosis. 2018; 4(1).
  • Liu Z, Yuan X, Fernandes G, Dziak R, Ionita C. N, Li C, .... The combination of nano-calcium sulfate/platelet rich plasma gel scaffold with BMP2 gene-modified mesenchymal stem cells promotes bone regeneration in rat critical-sized calvarial defects Stem Cell Research & Therapy. 2017; 8(1).
  • Laurel T, Perelman Karmon M, Nguyen D, Dziak, R.. Nanocalcium sulfate and collagen biomaterials: Effects on osteoblastic cells. (2017) Dent Oral Craniofac Res, 3(4): 2-5: doi: 10.15761/DOCR.1000210. Dent Oral Craniofac Res. 2017; 3(4).
  • Tyler Laurel, Mally Perelman Karmon, Dinh Nguyen and Rosemary Dziak. Nanocalcium sulfate and collagen biomaterials: Effects on osteoblastic cells. Dent Oral Craniofac Res. 2017; 3(4).
  • Ali, H.S., Baier, R.E., Dziak, R. & Andreana, S.. Promotion of Cells to Close Gaps and Encourage Cell Coverage, by Radio Frequency Glow Discharge Treatment.. Journal of Biomedical Materials Research Part A.. 2017; 105(1).
  • Dziak R, Ciancio SG, Maddi A. Nano-Calcium Sulfate as a Local Delivery System for Antibiotics. Int J Dent Oral Health. 2017; 3(2).
  • Fernandes, G., Barone, A. W., & Dziak, R.. The effect of ascorbic acid on bone cancer cells in vitro. Cogent Biology. 2017; 12883.
  • Yuan X, Smith RJ, Guan H, Ionita CN, Khobragade P, Dziak R, Liu Z, Pang M, Wang C, Guan G, Andreadis S, Yang S. Hybrid Biomaterial with Conjugated Growth Factors and Mesenchymal Stem Cells for Ectopic Bone Formation. Tissue Eng Part A. 2016.
  • Barone A, Morrell A, Dziak R. Fabrication and Characterization of NanoCalcium Sulfate and Human Platelet Lysate as a Growth Factor Delivery System. I. Int J Dent Oral Health. 2016; 2(2).
  • Fernandes, G., Wang, C., Yuan, X., Liu, Z., Dziak, R., & Yang, S.. Combination of Controlled Release Platelet-Rich Plasma Alginate Beads and Bone Morphogenetic Protein-2 Genetically Modified Mesenchymal Stem Cells for Bone Regeneration.. Journal of periodontology. 2016; 87(4).
  • Fernandes G, Barone, A , Dziak R. Effects of Verapamil on Bone Cancer Cells In Vitro. Journal of Cell Biology and Cell Metabolism,. 2016; 3.
  • He X, Dziak R, Mao K, Genco R, Swithart M, Li C, Yang S. Integration of a Novel Injectable Nano Calcium Sulfate/Alginate Scaffold and BMP2 Gene-Modified Mesenchymal Stem Cells for Bone Regeneration. Tissue Eng Part A. 2013; 19(3-4).
  • Guo J, Wang Y, Cao C, Dziak R, Preston C, Guan G. Human Periodontal Ligament Cells Reaction on a Novel Hydroxyapatite-Collagen Scaffold. Dental Traumatology. 2012.
  • Park YB, Mohan K, Al-Sanousi A, Almaghrabi B, Genco RJ, Swihart MT, Dziak R. Synthesis and characterization of nanocrystalline calcium sulfate for use in osseous regeneration. Biomed Mater. 2011; 6(5).
  • Almazin SM, Ciancio S, Andreana S, Dziak R. The Effect of Doxycycline Hyclate, Chlorhexidine Gluconate and Minocycline Hydrochloride on Osteoblastic Proliferation and Differentiation In Vitro. J Periodontol. 2009; 80(6).
  • Rao MV, Berk J, Almojaly SA, Goodloe III S, Margarone JE, Sullivan M, Dziak R. Effects of platelet-derived growth factor, vitamin D and parathyroid hormone on osteoblasts derived from cancer patients on chronic bisphosphonate therapy.. Int J Mol Med. 2009; 3.
  • Perinpanayagam H, Martin T, Mithal V, Dahman M, Marzec N, Lampasso J, Dziak R. Alveolar bone osteoblast differentiation and Runx2/Cbfa1 expression. Arch Oral Biol. 2006; 51(5).
  • Kamer AR, El-Ghorab N, Marzec N, Margarone JE III, Dziak R. Nicotine Induced Proliferation and Cytokine Release in Osteoblastic Cells. Int J Mol Med. 2006; 17(1).
  • Bateman J, Intini G, Margarone J, Goodloe S, Bush PJ, Lynch SE, Dziak R. Platelet-derived growth factor enhancement of two alloplastic bone matrices. J Periodontol. 2005; 76(11).
  • Dziak R, Yang BM, Leung BW, Li S, Marzec N, Margarone J, Bobek L, Margarone JE. Effects of sphingosine-1-phosphate and lysophosphatidic acid on human osteoblastic cells. Prostaglandins Leukot Essent Fatty Acids. 2003; 68(3).
  • Dziak R, Yang, BM, Leung, BW, Li, S, Marzec, N, Margarone, J III, Bobek LA. Effects of Sphingosine-1-Phosphate and Lysophosphatidic Acid on Human Osteoblastic Cells. Prostaglandins Leukotrienes & Essential Fatty Acids. 2003; 68.
  • Intini G, Andreana S, Margarone JE, Bush PJ, Dziak R. Engineering a bioactive matrix by modifications of calcium sulfate. Tissue Eng. 2002; 8(6).
  • Lampasso JD, Marzec N, Margarone J, Dziak R, Margarone JE. Role of protein kinase C alpha in primary human osteoblast proliferation. J Bone Miner Res. 2002; 17(11).
  • Judith Lampasso, Marzec, N., Joseph Margarone, Rosemary Dziak. The Role of PKC Alpha in the Proliferation of Primary Human Osteoblastic Cells.. Journal of Bone and Mineral Research. 2002; 17.
  • Intini G, Andreana S, Margarone JE, Marzec N, Dziak R. Engineering a Bioactive Matrix by Modifications of Calcium Sulfate. Tissue Engineering. 2002; 8(6).
  • Lampasso JD, Margarone, J III, Marzec, N, Dziak R. Role of PKC Alpha in Regulation of Osteoblastic Cell Proliferation. Journal of Bone & Mineral Research. 2002; 17.
  • Intini G, Andreanna, S, Margarone, J III, Bush, P, Dziak R. Engineering a Bioactive Matrix by Modification of Calcium Sulfate. Tissue Engineering. 2002; 8.
  • Gang, M, Marzec, N, Dziak R. The Effects of Insulin-Like Growth Factor-1 (IGF-I) on Osteoblastic Cells: Role of Voltage-Activated Calcium Channels. International Journal of Oral Biology. 2001.
  • Lampasso J, Kamer, A, Margarone, J III, Dziak R. Sphingosine-1-Phosphate Effects on PKC Isoform Expression in Human Osteoblastic Cells. Prostaglandins, Leukotrienes & Essential Fatty Acids. 2001; 65.
  • Carpio, LC, Shiau, H, Dziak R. Changes in Sphingolipid Levels Induced by Epidermal Growth Factor in Osteoblastic Cells. Effects of These Metabolites on Cytosolic Calcium Levels. Prostaglandins Leukotrienes & Essential Fatty Acids. 2000; 62.
  • Stephan E, Renjen R, Lynch SE, Dziak R. Platelet-Derived Growth Factor Enhancement of a Mineral-Collagen Bone Substitute. J Periodontol. 2000; 71.
  • Lampasso JD, Intini G, Dziak R. Effects of 1a25 Dihydroxyvitamin D3 on PKC Isoform Expression in Normal Rat Osteoblastic Cells.. Int J Oral Biol. 2000; 25(F427).
  • Loza JC, Carpio LC, Bradford PG, Dziak R. Molecular characterization of the alpha1 subunit of the L type voltage calcium channel expressed in rat calvarial osteoblasts. J Bone Miner Res. 1999; 14(3).
  • Loza, JC, Carpio, LC, Bradford, P, Dziak R. Molecular Characterization of the Alpha 1 Subunit of the L Type Voltage Calcium Channel Expressed in Rat Calvarial Osteoblasts. Journal of Bone & Mineral Research. 1999; 14.
  • Stephan E, Jiang D, Lynch S, Bush P, Dziak R. Anorganic Bovine Bone Supports Osteoblastic Cell Attachment and Proliferation. J Periodontol. 1999; 70.
  • Jiang D, Dziak R, Lynch SE, Stephan E. Modification of An Oseoconductive Anorganic Bovine Bone Mineral Matrix with Growth Factors. J Periodontol. 1999; 70.
  • Carpio LC, Stephan E, Kramer A, Dziak R. Sphingolipids Stimulate Cell Growth via MAP Kinase Activation in Osteoblastic Cells. Prostaglandins Leukotrienes and Essential Fatty Acids. 1999; 61.
  • Carpio, LC, Dziak R. Phosphatidic Acid Effects on Cytosolic Calcium and Proliferation in Osteoblastic Cells. Prostaglandins Leukotrienes & Essential Fatty Acids. 1998; 59.
  • Carpio, L, Dziak R. Activation of Phospholipase D Signaling Pathway by Epidermal Growth Factor in Osteoblastic Cells. Journal of Bone & Mineral Research. 1998; 13.
  • Dolce, C, Kinniburgh, AJ, Dziak R. Immediate Early-Gene Induction in Rat Osteoblastic Cells After Mechanical Deformation. Archives of Oral Biology. 1996; 41.
  • Kirkwood, KL, Dziak R, Bradford, PG. Inositol Trisphosphate Receptor Gene Expression and Hormonal Regulation in Osteoblast-Like Cell Lines and Primary Osteoblastic Cell Cultures. Journal of Bone and Mineral Research. 1996; 11.
  • Zhang, W, Dziak R. Tumor Necrosis Factor Alpha Stimulates Arachidonic Acid Metabolism in Human Osteoblastic Osteosarcomal Cells. Prostaglandins, Leukotrienes & Essential Fatty Acids. 1996; 54.
  • Loza, JC, Carpio, LC, Dziak R. Osteoprosis and Its Relationship to Oral Bone Loss. Current Opinions in Periodontology. 1996; 3.
  • Kirkwood KL, Dziak R, Bradford PG. Inositol trisphosphate receptor gene expression and hormonal regulation in osteoblast-like cell lines and primary osteoblastic cell cultures. Journal of Bone and Mineral Research. 1996; 11.
  • Carpio L, Dziak R. Plasminogen Activators in Osteoblastic Cells. 1995.
  • Zhang W, Dziak R, Aletta JM. Effects of EGF and ERK-Phosphorylation in Osteoblastic Cells: Regulation by Protein Kinase C. Journal Cellular Physiology. 1995; 162.
  • Loza, J, Carpio, L, Lawless, G, Marzec, N, Dziak R. Role of Extracellular Calcium Influx in EGF-Induced Osteoblastic Cell Proliferation. Bone and Mineral. 1995; 16.
  • Loza, J, Marzec, N, Semasko, S, Dziak R. Role of Experimental Growth Factor-Induced Membrane Depolarization. Cell Calcium. 1995; 17.
  • Loza, J, Stephan, E, Dolce, C, Dziak R, Simasko, S. Calcium Currents in Ostroblastic Cells: Dependence Upon Cellular Growth Stage. Calcified Tissue International. 1994; 55.
  • Stephan E, Dziak R. Effects of Genisteen Tryphositin and Pertussis Toxin on EGF-Induced Mitogenesis in Primary Culture and Clonal Osteoblastic Cells. Calcif Tissue Int. 1994; 54.
  • Zhang, W, Dziak R. Effects of Interleukin-1 Beta on Arachidonic Acid Metabolism in Osteoblastic Asteosarcomal Cells. Prostaglandins, Leukotrienes and Essential Fatty Acids. 1993; 49.
  • Dziak R. Biochemical and Molecular Mediators of Bone Metabolism. J Periodontol. 1993; 64.
  • Kohl, AC, Tatakis, DN, Hansen, C, Dziak R. Effects of Interleukin-1, Tumor Necrosis Factor-B and Forskolin on Tissue Plasminogen Activator Activity in Human Osteoblastic Osteosarcoma Cells. Calcified Tissue International. 1992; 50.
  • Tatakis, DN, Dolce, C, Hagel-Bradway, S, Dziak R. Bradykinin Stimulated Second Messenger Systems in Osteoblastic Cells. Evidence for B2 Receptors. Bone and Mineral. 1992; 40.
  • Falsafi R, Tatakis DN, Hagel-Bradway S, Dziak R. Effects of inositol trisphosphate on calcium mobilization in bone cells. Calcif Tissue Int. 1991; 49(5).
  • Ren, W, Dziak R. Effects of Leukotrienes on Osteoblastic Cell Proliferation. Calcified Tissue International. 1991; 49.
  • Falsafi, R, Tatakis, DN, Hagel-Bradway, S, Dziak R. Effects of Inositol 1, 4, 5 Triphosphate on Calcium Mobilization in Isolated Bone Cells. Calcified Tissue International. 1991; 49.
  • Tatakis, DN, Dolce, C, Dziak R, Fenton, JW. Thrombin Effects on Osteoblastic Cells II. Structure-Function Relationships. Biochemical and Biophysical Research Communications. 1991; 174.
  • Tatakis, DN, Schneeberg, G, Dziak R. Recombinant Interleukin-1 Stimulates Prostaglandin E2 Production by Osteoblastic Cells: Role of Calcium and cAMP. Lymphokine Cytokine Research. 1991; 10.
  • Ren, W, Kinniburgh, AJ, Dziak R. Regulation of c-myc Protooncogene Expression by Arachiodonic Acid Metabolites. Calcified Tissue International. 1991; 50.
  • Hagel-Bradway, S, Dziak R. Effects of Phorbol Esters on PGE2-Induced Effects in Osteoblastic Cells. Calcified Tissue International. 1991; 48.
  • Shapiro, S, Tatakis, D, Dziak R. Effects of Tumor Necrosis Factor alpha on Parathyroid Hormone-Stimulated Increases in Osteoblastic Cell Cyclic AMP. Calcified Tissue International. 1990; 46.
  • Hagel-Bradway, S, Dziak R. Biochemical and Cellular Mechanisms of Bone Cell Metabolism: A Review. J Oral Pathology. 1989; 18.
  • Mohammed, A, Tatakis, D, Dziak R. Leukotrienes in Orthodontic Tooth Movement. American Journal of Orthodontics. 1989; 95.
  • Tatakis, D, Dolce, C, Dziak R. Thrombin's Effects on Osteoglastic Cells: I. Cytosolic Calcium and Phosphoinositides. Biochem. Biophys. Res. Comm.. 1989; 164.
  • Tatakis DN, Dziak R. Recombinant Human Lymphotoxin Effects of Osteoblastic Cells. Biochem Biophys Comm. 1989; 162.
  • Tatakis, D, Schneeberger, G, Dziak R. Recombinant Interleukin-1 Stimulates Prostaglandin E2 Production by Osteoblastic Cells. Calcified Tissue International. 1988; 42.
  • Dziak R, Vernillo, A, Rifkin, B. Effects of Phenytoin on Osteoblastic Cell Calcium. J Bone Mineral Research. 1988; 3.
  • Dziak R, Farr, D, Zoghby, G, Weinfeld, N. The Effects of Calmodulin Antagonists on Prostaglandin E2 - Induced Responses in Rat Calvarial Bone Cells. Archives of Oral Biology. 1986; 31.
  • Farr, DH, Brown, MJ, Weinfeld, N, Dziak R. Effects of Prostaglandin on Rat Calvarial Bone Cell Calcium. Archives of Oral Biology. 1984; 29.
  • Robin, JC, Brown, MJ, Weinfeld, N, Dziak R. Benzo (B) Thiophene-2-Carboxylic Acid: Calcium Uptake and Cyclic AMP Production in Isolated Bone Cells. Calcified Tissue International. 1984; 36.
  • Dziak R, Hurd, D, Brown, MJ, Miyasaki, KT, Weinfeld, N, Hausmann E. Prostaglandin E2 Binding and Cyclic AMP Production in Isolated Bone Cells. Calcified Tissue International. 1983; 35.
  • Dziak R, Rowe DJ, Brown MJ, Hausmann E. Effects of Synthetic Muramyl Dipeptide on Bone Metabolism. Arch Oral Bio. 1983; 27.
  • Nair BC, Mayberry WR, Dziak R, Chen PB, Levine MJ, Hausmann E. Biological effects of a purified lipopolysaccharide from Bacteroides gingivalis.. J Periodontal Res. 1983; 18.
  • Shlossman, M, Brown, M, Shapiro, E, Dziak R. Calcitonin Effects on Bone Cell Calcium. Calcified Tissue International. 1982; 34.
  • Robin, JC, Brown, MJ, Weinfeld, N, Dziak R. Prostacyclin: Effects on Cyclic AMP in Bone Cells. Research Communications in Chemical Pathology and Pharmacology. 1982; 35.
  • Hausmann E, Nair, BC, Knox, KW, Broady, KW, Wicken, AJ, Brown, MJ, Dziak R. Partial Purification and Characterization of the Bone Resorption Factor from Actinomyces viscosus. Calcified Tissue International. 1981; 34.
  • Dziak R, Chang, YW, Humphries, D, Lloyd, W, Wells, H, Schmid, K, Nimberg, R. Effects of a Bone Resorptive Factor from Human Cancer Fluid on Bone Cell Calcium and Cyclic AMP. Calcified Tissue International. 1980; 30.
  • Dziak R, Hausmann E, Chang YW. Effects of Lipopolysaccharide on Bone Cell Calcium and Cyclic AMP. Archs Oral Biol. 1979; 24.
  • Dziak R. Effects of Vitamin D3 Metabolites on Bone Cell Calcium. Calcified Tissue International. 1978; 26.
  • Dziak R, Stern, PH. Effects of the Lonophore, A23187, on Fetal Rat Bone Organ Cultures and Isolated Bone Cells. Calcified Tissue Research. 1976; 22.
  • Feldman, D, Dziak R, Koehler, R, Stern, PH. Cytoplasmic Glucorticoid Receptors in Bone Cells. Endocrinology. 1975; 96.
  • Dziak R, Stern, PH. Calcium Transport in Isolated Bone Cells. III. Effects of Parathyroid Hormone and 3‘, 5‘, AMP. Endocrinology. 1975; 97.
  • Dziak R, Stern PH. Parathyromimetic Effects of the Lonophore, A23187, on Bone Cells and Organ Cultures. Biochem Biophys Res Comm. 1975; 65.
  • Dziak R, Brand JS. Calcium Transport in Isolated Bone Cells. I. Bone Cell Isolation Procedures. J Cell Phys. 1974; 84.
  • Dziak R, Brand JS. Calcium Transport in Isolated Bone Cells. II. Calcium Transport Studies. J Cell Phys. 1974; 84.
  • Ali, H.S., Baier, R.E., Dziak, R. & Andreana. Promotion of Cells to Close Gaps and Encourage Cell Coverage, by Radio Frequency Glow Discharge Treatment.. Journal of Biomedical Materials Research Part A...
  • Dziak R, Hausmann E, Chang YW. Effects of Lipopolysaccharide on Bone Cell Calcium and Cyclic AMP. Archs Oral Biol. ; 24.
  • Dziak, R.; Y.W. Chang, Humphries, D.; Lloyd, W.; Wells, H.; Schmid, K.; Nimberg, R.. Effects of a Bone Resorptive Factor from Human Cancer Fluid on Bone Cell Calcium and Cyclic AMP. Calcified Tissue International. ; 30.
  • Hausmann E, Nair BC, Knox KW, Broady KW, Wicken AJ, Brown M, Dziak R. Partial Purification and Characterization of the Bone Resorptive Factor from Actinomyces viscosus. Calcif Tiss Int. ; 34.
  • Dziak R, Hurd D, Brown MJ, Miyasaki KT, Weinfeld N, Hausmann E. Prostaglandin E2 Binding and Cyclic AMP Production in Isolated Bone Cells. Calcif Tiss Int. ; 35.
  • Dziak R, Rowe DJ, Brown MJ, Hausmann E. Effects of Synthetic Muramyl Dipeptide on Bone Metabolism. Arch Oral Bio. ; 27.
  • Farr, D.H., Brown, M.J., Weinfeld, N., Rosemary Dziak. Effects of Prostaglandin on Rat Calvarial Bone Cell Calcium. Archives of Oral Biology. ; 29.
  • Rosemary Dziak. Prostaglandins as Mediators of Bone Cell Metabolism in Calcium in Biological Systems. Plenum Publishing, New York..
  • Rosemary Dziak, Farr, D., Zoghby, G., Weinfeld, N.. The Effects of Calmodulin Antagonists on Prostaglandin E2-Induced Responses in Rat Calvarial Bone Cells. Archives of Oral Biology. ; 31.
  • Rosemary Dziak. Gum Gingiva in Encyclopedia of Human Biology. Academic Press..
  • Ren, W., Tatakis, D.N., Rosemary Dziak. Effects of leukotrienes on osteoblastic cells: Cytosolic calcium and cyclic AMP studies. Proceedings of Biological Mechanisms of Tooth Movement and Craniofacial Adaptation..
  • Rosemary Dziak. Role of Lipids in Osteogenesis Cell Signaling and Matrix Calcification in Biological Systems. CRC Press..
  • Carpio, L., Rosemary Dziak. Plasminogen Activators in Osteoblastic Cells. CRC Publications..
  • Gang, M., Marzec, N., Rosemary Dziak. The Effects of Insulin-like Growth Factor-1 (IGF-1) on Osteoblastic Cells: Role of Voltage-Activated Calcium Channels. International Journal of Oral Biology..
See all (91 more)

Books and Book Chapters:

  • Dziak R. Role of Lipids in Osteogenesis Cell Signaling and Matrix Calcification in Biological Systems. Calcification in Biological Systems. 1992.
  • Dziak R. Gum (Gingiva). Encyclopedia of Human Biology. 1989.
  • Dziak R. Prostaglandins as Mediators of Bone Cell Metabolism.. Calcium in Biological Systems. 1985.
  • Hausmann E, Nair BC, Dziak R. Bacterial Components Which Result in Bone Loss.. Host Bacterial Interactions in Periodontal Diseases. 1981.

Abstracts:

  • Al-Hashemi JY, Andreana S, Baier R, Dziak R, Bairam L. Osteoblasts‘ Response to Date-Expired Implants Renewed by H2O2 Gas Plasma. IADR Abstracts. 2014.
  • Al-Hashemi J, Baier R, Andreana S, Dziak R, Bairam L. Out of date dental implants; Surface optimization and re-sterilization.. J Dent Res. 2013.
  • Guo J, Wang Y, Cao C, Dziak R, Preston C, Guan G. Human Periodontal Ligament Cells Reaction on a Novel Hydroxyapatite-Collagen Scaffold. Dental Traumatology. 2012.
  • Hyun P, Al-Mojaly SA, Goodloe III S, Margarone III JE, Ciancio SG, Dziak R. Effects of Alendronate on Alkaline Phosphotase in Osteoblastic Cells. J Dent Res. 2009.
  • Berk J, Dziak R. Effects of bisphosphates (Etidronate) on human alveolar bone derived osteoblasts. J Dent Res. 2008.
  • Park Y, Dziak R, Cho M-I, Bobek LA, Swihart M, Genco R. nano-particles Calcium Sulfate, Growth Factor delivery scaffold for bone regeneration. J Dent Res. 2008.
  • Park Y, Parthasarthy K, Margarone III J, Schifferle R, Perinpanayagam H, Dziak R. Effects of EMD on Cytokine Production by Human PDL Fibroblasts. J Dent Res. 2007.
  • Smith CJ, Dziak R, Bernat JE. Toxicity of Formocresol and Ferric Sulfate on Proliferating Osteoblasts. J Dent Res. 2006.
  • Smith CS, Dziak R, Bernat JE. Toxicity of formocresol and ferric sulfate on proliferating osteoblasts. Pediatr Dent. 2006.
  • Molon J, Andreana S, Dziak R, Perinpayagam H, Park Y. Metal Surface Topography Effects on Human Gingival Fibroblasts. J Dent Res. 2006.
  • Intini G, Andreana S, Dziak R, Bobek LA. CS-Platelet for Bone Gene Therapy with RUNX2/Cbfa1 Gene. J Dent Res. 2005.
  • Martin T, Mithal V, Dahman M, Lampasso JD, Dziak R, Ciancio SG, Perinpanayagam H. Human Osteoblast Differentiation and RUNX2 Expression.. J Dent Res. 2005.
  • Stansbury CD, Nabadalung D, Dziak R, Lampasso J.. Protein kinase C (PKC) Expression Profile in Differentiating MC3T3-E1 Cells.. J Dent Res. 2005.
  • Sleilati J, Park Y, Intini G, Marzec N, Lampasso J, Perinpanayagam H, Dziak R. Effects of enamel matrix protein on human osteoblastic cells. J Dent Res. 2005.
  • Dahman M, Perinpanayagam H, Chen W, Marzec N, Dziak R, Lampasso J. Inhibition of p38 MAPK reduces alkaline phosphotase in differentiating osteoblasts. J Dent Res. 2005.
  • Gleason JF, Lampasso JD, Dziak R, Nabadalung D. Effects of cranioplastic relining resins on proinflammatory cytokine production. J Dent Res. 2005.
  • Nabadalung D, Park Y, Gleason J, Dziak R, Lampasso J. Upregulated GMCSF Production by Human Osteoblasts Exposed to Urethane Dimethacrylate.. J Dent Res. 2005.
  • Bateman J, Dziak R, Lynch SE. Platelet-derived Growth Factor Enhancement of an Osteoconductive Matrix. J Dent Res. 2005.
  • Lampasso JD, Park Y, Sebastian A, Dziak R, Perinpanayagam H. Effects of Emdogain on Cytokine Production by Human Osteoblastic and Periodontal Ligament Cells.. J Dent Res. 2005.
  • Park Y, Margarone JE, Goodloe III S, Lampasso JD, Perinpanayagam H, Andreana S, Dziak R. Emdogains Effects on Protein Kinase-C Expression on Human Periodontal Fibroblasts. J Dent Res. 2005.
  • Molon J, Andreana S, Park Y, Bush PJ, Dziak R. Metal Surface Topography Effects on Human Gingival Fibroblasts. J Dent Res. 2005.
  • Park Y, Nabadalung D, Perinpanayagam H, Lampasso JD, Andreana S, Dziak R. Effects of EMD on the Expression of Cytokines in HPLF Treated with P. Gingivalis-LPS. J Periodontol. 2005.
  • Intini G, Andreana S, Dziak R, Bobek LA. Calcium sulfate and PRP for bone gene therapy with RUNX2/Cbfa1 gene. The Genco Symposium, Buffalo, NY September 2004. State University of New York at Buffalo, Buffalo, NY. 2004.
  • Intini G, Andreana S, Dziak R, Bobek LA. Bone Regenerative Gene Therapy with Calcium Sulfate and PRP. J Periodontol. 2004.
  • Andreana S, Intini G, Natiella J, Bobek LA, Dziak R. Bone Grafting with Calcium Sulfate and PRP: Histological Findings in a Non-Human Primate Model. J Periodontol. 2004.
  • Intini G, Andreana S, Dziak R, Bobek LA. Calcium Sulfate and PRP for Bone Gene Therapy with RUNX/2Cbfa1 Gene. Symposium Robert J Genco. 2004.
  • Intini F, Intini G, Bobek LA, Dziak R, Andreana S. Clinical Application of Calcium-Sulfate Activated PRP. J Periodontol. 2003; 74(11).
  • Intini G, Andreana S, Margarone JE, Bush P, Dziak R. Tissue-Engineering of Bone Graft Material: Modifications of Calcium Sulfate. J Dent Res. 2001; 80.
  • Intini G, Andreana S, Margarone JE, Bush P, Dziak R. Calcium Sulfate with PRP Favors Osteoblast Attachment. J Periodontol. 2001; 72(12).
  • Stephan E, Khodiery S, Kramer A, Jackson W, Intini G, Bush P, Marzed N, Dziak R. Effects of synsthetic nonceramic hydroxyapatite on human osteoblastic cells. J Dent Res. 2000; 79.
  • Stephan E, Caprio LC, Kamer A, Dziak R. Sphingolipids mitogenic effects on osteoblastic cells via MAPK activation. J Bone Min Res. 1999; SA.
  • Kirkwood KL, Dziak R, Bradford P. Inositol trisphosphate receptor subtype analysis in human osteosarcona cells.. J Dent Res. 1995; 74(318).
  • Kirkwood K, Dziak R, Bradford P. InsP3 receptor subtype analysis in human osteosarcoma cells.. J Dent Res. 1995; 74.
  • Kirkwood K, Dziak R, Bradford P. Selective expression of InsP3 receptor gene in human osteosarcoma cells.. J Dent Res. 1993; 72.
  • Lampasso JD, Dziak R. Sphingolipids Effects on the Mitogen Activated Protein Kinase Pathway in Osteoblastic Cells.. J Bone Miner Res. ; 14(1).
  • Lampasso JD, Bineyard N, Marzec N, Dziak R. Expression Pattern of a & y PKC in G292 Osteosarcoma Cells.. J Dent Res. ; 2618.
  • Lampasso JD, Dziak R. 1a25(OH)2D3 Effects on PKC * Expression in Normal Rat Osteoblastic Cells.. J Bone Miner Res. ; 12(1).
See all (27 more)

Professional Memberships:

  • International Association for Dental Research (1989–present)
  • American Society for Bone and Mineral Research; Program Committee (1981–present)
  • American Association for the Advancement of Science (1981–present)
  • Endocrine Society (1981–present)
  • New York Academy of Science

Presentations:

  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (2002)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (2001)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (2000)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High School (1999)
  • "Effects of Nicotine on Osteoblastic Cells" IADR Meeting, IADR (1998)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (1998)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (1997)
  • "Careers in Science" Buffalo Area Middle and High Schools, Buffalo Area Middle and High Schools (1996)
  • "EGF Effects on Osteoblastic Cells" Buffalo General Hospital, Buffalo General Hospital, Department of Medicine, Cell Adhesion Group (1995)
  • "Calcium Currents in Osteoblastic Cells" University at Buffalo, SUNY-Buffalo, Department of Biochemical Pharmacology (1994)
  • "Studies with Isolated Bone Cells" Niagara Frontier Science Supervisors Science Day for High Schools, Niagara Frontier Science Supervisors Science Day for High Schools, Niagara Frontier Science Supervisors Science Day for High Schools (1993)
  • "Calcium and Osteoporosis" American Red Cross, American Red Cross, Buffalo Chapter (1992)
  • "Calcium Studies with Bone Cells" University at Buffalo, SUNY-Buffalo, Department Physical Therapy & Exercise Science (1992)
  • "Signal Transduction Mechanisms in Osteoblastic Cells" New Jersey School of Medicine, New Jersey School of Medicine, Department of Anatomy (1991)
  • "Bone and Boneheads" Canisius College, Canisius College, High School Students (1991)
  • "Advances in Arthritis Research" Arhritis Foundation of W.N.Y., Arthritis Foundation of W.N.Y., Awards Banquet (1990)
  • "Bone and Boneheads" Canisius College, Canisius College, High School Students (1989)
  • "Calcium and Your Bones" Neuman Club, Neuman Club (1989)
  • "Second Messenger Systems in Prostaglandin E2 Effects of Osteoblastic Cells" Veterans Administration Hospital, Veterans Administration Hospital, Department of Medicine (1988)
  • "Prostaglandins Effects on Bone Cell Metabolism" IADR Meeting, IADR (1988)
  • "Calcium Exercise and Osteoporosis" Double Knots - Society for Marrieds Over 50, Double Knots, Society for Marrieds over 50 (1987)
  • "Postgraduate Opportunities in Oral Biology" Special Conference on Minorities in Biomedical Research, NIH, NIH (1987)
  • "Calcium and Osteoporosis" Amherst Senior Citizens Society, Amherst Senior Citizens Society (1986)
  • "Craniofacial Biology I" Molecular Mediators IADR/AADR General Session, IADR/AADR, Molecular Mediators - General Session (1985)
  • "Prostaglandins and Bone Cell Regulation" 67th Annual Meeting of Federation of American Societies for Experimental Biology, Intersociety Symposium on Bone Regulatory Factors (1983)
  • "Mononuclear Osteoclastic Cells" 5th Annual Meeting of American Society for Bone and Mineral Research, 5th Annual Meeting of American Society for Bone and Mineral Research, 5th Annual Meeting of American Society for Bone and Mineral Research (1983)
  • "Dietary Calcium and Osteoporosis" Women‘s Jewish Organization, Women‘s Jewish Organization, Hadassah (1981)
  • "Bone Cell Calcium Studies" 3rd Annual Meeting American Society for Bone and Mineral Research (1981)
  • "PTH action" 3rd Annual Meeting of American Society for Bone and Mineral Research (1981)
  • "Calcium Bones and Aging" East High School, Buffalo Vocational Technical School (East High School), Junior High School Students (1981)
  • "Target Cell Responses" VII International Parathyroid Conference (1980)
  • "Effects of Vitamin D Metabolites on Bone Cell Calcium" University at Buffalo, SUNY-Buffalo School of Medicine, Department of Gastroenterology (1980)
  • "To Your Health" Channel 7, T.V. Series, Channel 7, T.V.series (1978)
See all (23 more)

Service Activities:

  • School of Dental Medicine Promotion and Tenure Committee; Member (2012–2017)
  • School of Dental Medicine Thesis Honors Committee; Member (2007)
  • School of Dental Medicine Minority Student Affairs Committee; Member (2007)
  • School of Dental Medicine Appeals Board; Member (2001–2017)
  • School of Dental Medicine Admissions Committee; Member (2000–2017)
  • School of Dental Medicine Research Committee; Member (1984–1987)
  • Oral Biology, School of Dental Medicine Graduate Committee, D.D.S./Ph.D.; Director (1979–1984)
  • Editorial Board, Journal of Oral Biology; Executive Board (2016–2017)
  • Executive Editor; Internation Journal of experimental Dental Science; Advisor for publications in International Journal of Experimental Dental Science; Editorial Director (2015–2018)
  • Editorial Board Immunological Investigations; Advisor/ Guest editor for the journal of Immunological Investigations; Editorial Board Member (2010–2018)
  • IADR Program Comittee, Mineralized Tissue Meeting; Committee Member (1989)
  • American Society for Bone and Mineral Research; Awards Committee; Committee Member (1984)
  • American Society for Bone and Mineral Research; Education Committee; Committee Member (1982)
  • American Society for Bone and Mineral Research; Program Committee; Committee Member (1981)
  • International Journal of Oral Biology; Editorial Board Member (1981–present)
  • Journal of Periodontology; Editorial Board Member (1981–present)
  • Open Dental Journal; Editorial Board Member (1981–present)

School News:

In the Media:


Clinical Specialties:

Clinical Offices:

Insurance Accepted:



Contact Information

Foster Hall
Room 318
3435 Main Street
Buffalo, NY 14214
Phone: (716) 829-3827
Fax: (716) 829-3942
rdziak@buffalo.edu