I began my career as a general Medical Technologist and eventually specialized in clinical bacteriology in local hospital. I returned to school to earn an MS in Medical Technology specializing in Microbiology. I continued to work weekends in the hospital while working as a research technician in immunodermatology. I pursued further graduate work and earned a PhD degree in Microbiology from UB. During my thesis work I became interested in molecular mechanisms of infectious disease. As a post-doc I focused on characterizing the genes of the fimbrial operon and biofilm formation by the periodontopathogen Aggregatibacter actinomycetemcomitans. These studies expanded into gene regulation in A. actinomycetemcomitans by small non-coding sRNA. We have recently used RNA-Seq to investigate the effect of amylase on Streptococcus gordonii. Whole genome sequencing has been used to explore the phylogeny of amylase-binding proteins in various Streptococcal strains. We are also discovering potential new functions for amylase-binding protein A from Streptococcus gordonii and pursuing new experimental evidence. We are also working on oral microbiome projects with clinical physicians and dentists.
Education and Training:
PhD, Microbiology, University at Buffalo (1995)
MS, Medical Technology, Microbiology Specialty, University at Buffalo (1984)
BS, Medical Technology, University at Buffalo (1975)
Research Professor, University at Buffalo (2018-present)
Research Associate Professor, Oral Biology, State University of New York at Buffalo (2005–2017)
Research Assistant Professor, Oral Biology, State University of New York at Buffalo (1998–2005)
Post-Doctoral Fellow, Oral Biology, State University of New York at Buffalo (1994–1998)
Research Assistant, Oral Biology, State University of New York at Buffalo (1994)
Research Assistant, Microbiology and Immunology, State University of New York at Buffalo (1986–1994)
Medical Technologist, St. Mary‘s Hospital (1975–1991)
Research Technician, Microbiology and Immunology, State University of New York at Buffalo (1985–1986)
Awards and Honors:
Dental Student Research Mentor Award (2016)
Listed in Who's Who in America (2010)
American Society for Microbiology Student Travel Award (1994)
Listed in Who's Who Among Students in American Universities and Colleges (1992)
American Society for Microbiology Student Travel Award (1990)
Erwin Neter Award from WNY American Society of Microbiology (1990)
Bioinformatics: Analysis of RNA-seq and DNA-seq data.
Microbiologist: Bacterial adhesion mechanisms, biofilm studies, protein analysis, regulation of biofilms, and molecular biology. Bioinformatic and microbiome studies.
Grants and Sponsored Research:
April 2012–April 2017 Amylase Binding and Gene Expression in S. gordonii. NIH-NIDCR Role: Co-Investigator $1,250,000
April 2004–December 2008 Amylase-Binding Streptococci, Dental Plaque and Caries NIH, USPHS Role: Co-Investigator $1,532,810
July 2004–June 2007 Oral Health and Ventilator-Associated Pneumoniae NIH, USPHS Role: Co-Investigator $1,140,607
July 2004–January 2007 New Salicylanilides to Treat Oral Diseases NIH/SBIR Role: Co-Investigator
January 2002–December 2003 Studies of the flp operon in A. actinomycetemcomitans National Institute for Dental & Craniofacial Research Role: Principal Investigator $156,000
Haraokopakis E, Haase EM, Scannapieco F, Albzreh H, Hajishengallis G. Inhibition of Proinflammatory Activities of Major Periodontal Pathogens by Aqueous Extracts from Elder Flower (Sambucus nigra).. J Periodontol. 2006; 77.
Bernstein JM, Haase EM, Dryja D, Wolf J, Briles D, Wilding G. Bacterial Interference of Penicillin-Sensitive and Penicillin-Resistant Streptococcus pneumoniae by Streptococcus oralis in an Adenoid Organ Culture: Implications for the Treatment of Recurrent Upper Respiratory Tract Infections in Children and Adults.. Ann Otol Rhinol Lyarngol. 2006; 115.
Tanzer JM, Grant L, Thompson A, Li L, Rogers JD, Haase EM, Scannapieco FA. Amylase-Binding Protein A (AbpA) and B (AbpB) Differentially Affect Colonization of Rats‘ Teeth by Streptococcus gordonii.. Microbiol. 2003; 149.
Paju Susanna, Bernstein JM, Haase EM, Scannapieco FA. Molecular Analysis of Bacterial Flora Associated with Chronically Inflamed Maxillary Sinuses.. J Med Microbiol. 2003; 52.
Haase EM, Stream JO, Scannapieco FA. Transcriptional Analysis of the 5‘-Terminus of the flp Fimbrial Gene Cluster from Actinobacillus actinomycetemcomitans.. Microbiol. 2003; 149.
Tanzer JM, Baranowski LK, Scannapieco FA, Rogers JD, Haase EM. Oral Colonization and Cariogenicity of Streptococcus gordonii in Specific Pathogen-free TAN:SPFOM(OM)BR Rats Consuming Starch or Sucrose Diet.. Arch Oral Biol. 2000; 46.
Brown AE, Rogers JD, Haase EM, Zelasko PM, Scannapieco FA. Prevalence of the Amylase-Binding Protein A Gene (abpA) in Oral Streptococci.. J Clin Microbiol. 1999; 37.
Haase EM, Zmuda JL, Scannapieco FA. Identification and Molecular Analysis of Rough-Colony-Specific Outer Membrane Proteins of Actinobacillus actinomycetemcomitans.. Infect Immun. 1999; 67.
Rogers JD, Haase EM, Brown AE, Douglas CWI, Gwynn JP, Scannapieco FA. Identification and Analysis of a Gene (abpA) Essential for Amylase Binding to Streptococcus gordonii.. Microbiol. 1998; 144.
Haase EM, Yi K, Morse GD, Murphy TF. Mapping of Bactericidal Epitopes on the P2 Porin Protein of Nontypeable Haemophilus influenzae.. Infect Immun. 1994; 62.
Haase EM, Campagnari AA, Sarwar J, Shero M, Wirth M, Cumming CU, Murphy TF. Strain-Specific and Immunodominant Surface Epitopes of the P2 Porin Protein of Nontypeable Haemophilus influenzae.. Infect Immun. 1991; 59.
Heo S-M, Haase EM, Scannapieco FA. Genetic Relationship Between Respiratory Pathogens Isolated from the Mouth and Lung.. J Dent Res. 2008; 87.
Haase EM, Dunn J, Evans R, Scannapieco FA. Evaluation of Antimicrobial Efficacy Against Biofilms Using the Calgary Biofilm Device.. 4th ASM Conference on Biofilms. 2007.
Heo S-M, Haase EM, Scannapieco F. Molecular Epidemiology of Plaque and Lung Bacteria from Ventilated Patients.. J Dent Res. 2007; 86.
Haase EM, Legler R, Bonstein T, Bush PJ, Scannapieco FA. An in vitro Model Assessing Tooth Whitening Agent Effectiveness.. J Dent Res. 2004; 83.
Paju S, Haase EM, Tanzer JM, Scannapieco FA. Prevalence of the Gene Encoding Amylase-Binding Protein B, a Putative Peptidase, in Oral Streptococci.. J Dent Res. 2003; 82.
Haase EM, Palmer RJ Jr, Wang Y, Chen C, Kolenbrander P, Scannapieco FA. Localization of the rough colony protein A (RcpA) of Actinobacillus actinomycetemcomitans by immunofluorescence.. J Dent Res. 2002; 81.
Western New York Branch of the American Association for Dental Research; Local branch of the national AADR whose mission is to provide continuing education to those interested in all branches of dental research. (2014–present)
American Dental Education Association; Professional Membership (2006)
International/American Association for Dental Research; Professional Membership. (1996–2006)
Western New York Branch of the American Society for Microbiology; Local branch of the national American Society for Microbiology whose mission is to provide continuing education for those interested in all aspects of microbiology. (1988–present)
American Society for Microbiology; Professional Membership (1988–present)
American Society for Clinical Pathologists (1975–2001)
"The oral microbiome in sickness and i health" Annual Western New York American Society of Microbiology Meeting, American Society of Microbiology, Western New York Branch (2018)
"Dental Plaque" Student Outreach, Zeptometrix, West Seneca Academy High School Students (2018)
"Dental Plaque" Student Outreach, Zeptometrix, West Seneca Academy High School Students (2017)
"So what is so interesting about amylase-binding Streptococci?" WNY AADR, AADR (2015)
"Transcriptional changes of Streptococcus gordonii amylase-binding protein (abpA) mutant in TSBY medium" Gordon Conference, Salve Regina University, Microbial Adhesion and Signal Transduction (2013)
"Studies of the Flp Locus of Actinobacillus actinomycetemcomitans" Seminar Series, University of Southern California, Periodontology (2003)
American Society for Microbiology; The Committee on Microbial Sciences (COMS) is a program planning committee for the National ASM for the annual general meeting MICROBE.; Committee Member (2019–present)
Search committee for core facility manager; Committee Member (2018)
St. Christopher Church, Religious Education; Office assistant for religious education classes. Assist in attendance, answering phone, and other needed tasks. Volunteer at annual Summerfest celebration.; Volunteer (2002–2004)
Western New York American Society for Microbiology; Current member of the WNY ASM executive committee. Served as Secretary-Treasurer for 3 years, president-elect 1 year, president 1 year, past president for 3 years.; Committee Member (2000–present)
Laboratory Assistant; Laboratory Assistant for the summer program for Ernest Witebsky Center for Immunology.; Volunteer (1988)
In the Media:
Foster Hall Room 109B 3435 Main Street Buffalo, NY 14214 Phone: (716) 829-2520 Fax: (716) 829-3942 email@example.com