Ding Xu PhD

Ding Xu

Ding Xu
PhD

Assistant Professor

Department of Oral Biology

School of Dental Medicine


Specialty/Research Focus

Oral Biology

Contact Information
109c Foster Hall
3435 Main St
Buffalo, NY 14214
Phone: 7168293509
dingxu@buffalo.edu



Education and Training:

  • Postdoctoral Fellow, Vascular Biology, Inflammation, University of California, San Diego (2011)
  • PhD, University of North Carolina (2007)
  • BS, Biochemistry, Central China Normal Universtiy (1999)

Employment:

  • Assistant Project Scientist, Cellular and Molecular Medicine, University of California, San Diego, School of Medicine (2011–2014)

Awards and Honors:

  • JBC/Herbert Tabor Young Investigator Award (2012)
  • Outstanding Poster Award at the Gordon Research Conference, Proteoglycans (2012)
  • The ASBMB 2012 Thematic Best Poster in Glycobiology, 2012 ASBMB Annual Meeting (2012)
  • American Heart Association postdoctoral Fellowship (2008)
  • American Heart Association Predoctoral Fellowship (2005)

Research Expertise:

  • Glycobiology
  • Heparan Sulfate
  • Inflammation
  • Structural Biology
  • Vascular Biology

Grants and Sponsored Research:

  • September 2018–June 2022
    In vitro Synthesis of Recombinant Heparan Sulfate
    NIH
    Role: Co-Principal Investigator
    $478,500
  • August 2017–June 2022
    Heparan Sulfate–Osteoprotegerin Interactions in Bone Remodeling
    NIH-NIAMS
    Role: Principal Investigator
    $1,748,745
  • January 2013–December 2014
    RAGE – Heparan Sulfate Interactions in Vascular Inflammation
    American Heart Association
    Role: Principal Investigator
    $140,000

Patents:

  • Sulfated oligosaccharides decrease sterile inflammation damage in the live A new sulfated heparin sulfate oligosaccharide displays protective effect on drug-induced liver damage. The compound likely inhibits the function of HMGB1, a common protein in regulating immune responses. This discovery can be applied for a wide range of diseases that are caused by over reaction of inflammation responses.

Journal Articles:

See all (14 more)

Professional Memberships:

  • American Society for Biochemistry and Molecular Biology (2012–present)
  • Society for Glycobiology (2009–present)
  • American Society for Matrix Biology (2008–present)
  • American Heart Association (2004–present)

Presentations:

  • "Deciphering Heparan sulfate-protein interactions in Bone remodeling and inflammation" (2018)
  • "Deciphering Heparan sulfate-protein interactions in Bone remodeling" (2017)
  • "Deciphering Heparan sulfate-protein interactions in Bone remodeling" (2017)
  • "Heparan sulfate in bone remodeling" (AADR) Buffalo Section, Lunch and Learn Seminar Series, University at Buffalo (2015)
  • "Heparan sulfate in inflammation and bone remodeling" Inviated talk, Roswell Park Cancer Institute (2015)
  • "Heparan Sulfate–Dependent Oligomerization of RAGE is essential for signal transduction" Vasculata 2013, North American Vascular Biology Organization (2013)
  • "Heparan Sulfate–Dependent Oligomerization of RAGE is essential for signal transduction" Gordon Research Conference, Glycobiology, Gordon Research Conference (2013)
  • "Heparan Sulfate–Dependent Oligomerization of RAGE–a novel target for therapeutic intervention" Invited presentation, School of Pharmacy, University of Arizona (2013)
  • "Inactivation of heparan sulfate 2-O-sulfotransferase accentuates neutrophil infiltration during acute inflammation in mice" 2012 ASBMB Annual Meeting, ASBMB (2012)
  • "Heparan Sulfate as a regulator of VEGF-induced vascular permeability" Gordon Research Conference, Vascular Cell Biology, Vascular Cell Biology (2009)

Service Activities:

  • Jacobs School of Medicine & Biomedical Sciences Admissions Committee; Member (2017–2019)
  • Oral Biology, School of Dental Medicine Graduate Committee, Thesis; Member (2017–2020)
  • Oral Biology, School of Dental Medicine Graduate Committee, Admissions; Member (2017–2019)
  • Oral Biology, School of Dental Medicine Graduate Committee, Preliminary Exams; Fellow (2017–2018)
  • School of Dental Medicine Student Research and Honors Committee; Member (2017–2019)
  • Oral Biology, School of Dental Medicine Graduate Committee, Preliminary Exams; Advisor (2016)
  • Oral Biology, School of Dental Medicine Graduate Committee, Preliminary Exams; Member (2015–2018)

School News:

In the Media:


Clinical Specialties:

Clinical Offices:

Insurance Accepted:



Contact Information

109c Foster Hall
3435 Main St
Buffalo, NY 14214
Phone: 7168293509
dingxu@buffalo.edu