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Stefan Ruhl  PhD, DDS

Department of Oral Biology

Professor, DDS, PhD

Specialty/Research Focus

Operative Dentistry; Oral Biology; Pediatric Dentistry; Periodontics

Faculty Research Profile



 

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Professional Memberships:

  • American Society for Microbiology (ASM) (2013)
  • Central European Division of the IADR (CED) (2013)
  • Society for Glycobiology (2008)
  • Consortium for Functional Glycomics (2008)
  • American Association for Dental Research (AADR) (2008)

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  • German Society for Biochemistry and Molecular Biology (GBM) • Studygroup Glycobiology (1997)
  • International Association of Dental Research (IADR) , Salivary Research Group, Microbiology and Immunology Interest Group (1995)
  • German Society of Dental, Oral, and Craniomandibular Sciences (DGZMK) • German Society for Operative Dentistry (DGZ) • German Society for Pediatric Dentistry and Prophylaxis (DGK) • Studygroup for Basic Science (AfG) (1995)
  • German Society for Immunology (1995)

Presentations:

  • The Salivary Proteome – Oral Microbiome Interface, Göttingen Spirit Summer School, University of Göttingen (2015)
  • Mining the Oral Microbiome for Novel Glycan-Binding Molecules, NIH Common Fund Glycoscience Kick-off Meeting, NIH (2015)
  • A Slippery Path to a Career in Oral Biology, UB BIO-STEM / CLIMB-UP Scientific Discovery Series, University at Buffalo (2015)
  • Activation of host neutrophils through sialic acid binding by Streptococcus gordonii, IADR General Session & Exhibition, IADR (2015)
  • Human lineage-specific traits in the salivary proteome, Inaugural Meeting of the International Society for Evolution, Medicine & Public Health, International Society for Evolution, Medicine & Public Health (2015)

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  • Salivary Control of Oral Microflora, IADR General Session, IADR (2015)
  • Human Lineage-Specific Traits in the Salivary Proteome, Gordon Research Conference "Salivary Glands and Exocrine Biology, Gordon Research Conferences (2015)
  • Custom-Designed Biomaterial Surface Coatings to Minimize Bacterial Colonization, Seminar, Ivoclar Vivadent (2014)
  • The Magical Properties of Spit, Biosciences Lecture (UB iSEED Recruitment), SUNY Geneseo (2014)
  • A Slippery Path to a Career in Oral Biology, UB BIO-STEM / CLIMB-UP Scientific Discovery Series (2014)
  • Human Lineage Specific Traits in the Salivary Proteome, IADR General Session & Exhibition, IADR (2014)
  • The Diagnostic Potential of Bacterial Glycan Recognition in Saliva, 2013 SPIE DSS (Defense + Security, Sensing + Technology) Meeting (2014)
  • Keynote: Studies on the Salivary Proteome - Oral Microbiome Interface, 43rd Annual Meeting & Exhibition of the AADR, AADR (2014)
  • The Salivary Proteome - Oral Microbiome Interface, Invited Seminar Lecture, University of Minnesota, School of Dentistry (2013)
  • How I Became a Research Scientist, UB BioSTEM Lecture Series - CLIMB UP (2013)
  • The Salivary Proteome - Oral Microbiome Interface, 50th Anniversary, UB Oral Biology Graduate Program (2013)
  • The Importance of Saliva for a Healthy Mouth, UB Discovery Seminar - Oral Biology, University at Buffalo (2013)
  • How does the Salivary Proteome Modulate Bacterial Adhesion?, Bagel Talk, University of Rochester, Center for Oral Biology, University of Rochester (2012)
  • The Importance of Saliva for a Healthy Mouth - from a Glycobiologist's Perspective, SACNAS National Conference, SACNAS (2012)
  • New Aspects in Cariology, UB SDM Back-to-School Conference (2012)
  • Binding between Human Salivary Components and Staphylococcus aureus, 41st Annual Meeting of the AADR, AADR (2012)
  • Control of Oral Biofilm Formation on Biomaterials, UB Department of Chemistry (2012)
  • Control of Oral Biofilm Formation on Biomaterials, UB Integrated Nanoscience Workshop (2012)
  • The Importance of Saliva for the Dentist, UB-SDM Continuing Education (2011)
  • How Saliva Mediates Bacterial Adhesion, The New Jersey Dental School (2011)
  • It's in the Spit:: The Diagnostic Potential of Saliva, Buffalo Niagara Dental Meeting (2009)
  • The Diagnostic Potential of Saliva, Continuing Dental Education, UB School of Dental Medicine (2008)
  • A proteomics-based search for bacterial recognition sites in human saliva, Invited lecture, Department of Microbiology and Immunology, University at Buffalo (2008)
  • A proteomics-based search for bacterial recognition sites in human saliva, Rochester Oral Biology Research Conference (2008)
  • Bakterielle Erkennungsstrukturen im menschlichen Speichelproteom, Invited lecture, Medical Faculty, University of Gottingen, Germany, University of Gottingen (2007)
  • Das menschliche Speichelproteom als Grundlage fur zukunftige Diagnostik, Deutscher Zahnarztetag 2007 (2007)
  • Kinderzahnheilkunde und Alterszahnmedizin - Ein Gegensatz, Invited lecture, Medical Faculty, University of Gottingen, Germany, University of Gottingen (2007)
  • Sticky spots in spit - a proteomics-based search for bacterial recognition sites in human saliva, Invited Lecture, Umea University, Sweden, Umea University (2006)
  • Adsorption of proteins and attachment of bacteria to biomaterial surfaces, International Symposium Material - Tissue Interactions (2006)
  • The importance of saliva, Visit of the Academia Conservativa Italiana, University of Regensburg (2006)
  • Wissenswertes fur den Zahnarzt uber Speichel, Workshop: Speichel - "ein ganz besonderer Saft" (2006)
  • Spot Spitting and Spit Spotting: A Proteomics-Based Search for Functional Aspects in Saliva, Invited lecture, University of Buffalo (2006)
  • Adsorption von Proteinen und Adhasion von Bakterien auf Modelloberflachen und klinischen Werkstoffen, Medizinische Fakultat, Universitat Regensburg (2005)
  • Adhasion von Bakterien auf Oberflachen zahnarztlicher Werkstoffe, Symposium der Arbeitsgemeinschaft fur Grundlagenforschung in der DGZMK (2005)
  • Bedeutung des Speichels fur ein gesundes Mundmillieu, Klinischer Arbeitskreis im Qualitatszirkel des ZBV Oberpfalz (2005)
  • Bestandteile des menschlichen Speichels und ihre Bedeutung, Institut fur Physikalische und Theroetische Chemie, Universitat Regensburg (2005)
  • Speichel-'ein ganz besonderer Saft, Medizinische Fakultat, Universitat Leipzig (2005)
  • Der Speichel als diagnostische Flussigkeit, Medizinische Facultat, Universitat Regensburg (2003)
  • Speichel als diagnostische Flussigkeit, 2.Regionalkonferenz des Vereins zur Forderung der wissenschaftlichen Zahnheilkunde in Bayern, Kloster Seeon (2003)
  • Grundlagen und Stategien zahnarztlicher Prophylaxe, Klinischer Arbeitskreis im Qualitatszirkel des ZBV Oberpfalz (2003)
  • Adhasin-vermittelte Interaktionen oraler Midroorganismen mit Strukturen der Mundhohle, Institut fur Medizinische Mikrobiologie, Friedrich-Schiller-Universitat Jena (2003)
  • Prophylaxe, mehr als nur Einfarben. Individualprophylaxe-Theorie und Praxis, 43. Bayerischer Zahnarztetag (2002)
  • Moderne Prophlyaxe: Moglichkeiten, Chancen, Grenzen. Bleichung von Zahnen. Kinderzahnheilkunde:Endodontologie, Zahnarztlicher Fortbildungskreis, Rottal-Inn e.V. (2002)
  • Adhasin-vermittelte Interaktionen von oralen Bakterien mit Strukturen der Mundhohle, Mikrobiologisch-Immunologisches Kolloquium, Univeritat Ulm (2002)
  • Immunologie der Mundhohle, Vorlesung Immunologie fur Zahnmediziner, Universitat Ulm (2002)
  • Der diagnostische Stellenwert des Speichels fur die Kinderzahnheilkunde, Medizinische Fakultat, Christian-Albrechts-Universitat zu Kiel (2002)
  • Proteine und Glykoproteine im Speichel: Funktionen und mogliche klinische Bedeutung, Zahn-, Mund- und Kieferklinik, Ludwig-Maximilians-Universitat Munchen (2001)
  • Der Speichel als eine diagnostische Flussigkeit, Zentrum fur Zahn-, Mund- und Kieferheilkunde, Rheinische Friedrich-Wilhelms-Universitat Bonn (2001)
  • Bleichung von Zahnen: Moglichkeiten und Grenzen, Klinischer Arbeitskreis im Qualitatszirkel des ZBV Oberpfalz (2001)
  • Moderne Prophylaxe: Moglichkeiten, Chancen, Grenzen, 15. Oberpfalzer Zahnarztetag (2001)
  • Adhasin-vermittelte Interaktionen oraler Mikroorganismen mit Strukturen der Mundhohle, Zentrum fur Biomaterialien an der Universitat Regensburg (2001)
  • Adhasin-vermittelte Interaktionen von oralen Bakterien mit Strukturen der Mundhohle, Medizinische Fakultat, Rheinisch-Westfalische Technische Hochschule (2001)
  • Salivary Proteins and Glycoproteins: Interactions with the Oral Microbial Flora and Possible Clinical Relevance, Oral Infection and Community Branch, National Institute of Dental and Craniofacial Research, NIH (2000)
  • Kinderbehandlung: Milchzahnendodontie, Klinischer Arbeitskreis im Qualitatszirkel des ZBV Oberpfalz (1998)
  • Proteine und Glykoproteine im Speichel: Funktion und klinische Relevanz, 39. Bayerischer Zahnarztetag 1998 (1998)
  • Role of Sialic Acids in the Adhesion of Oral Bacteria, Sialinsaure-Workshop, Biochemisches Institute, Christian-Albrechts-Universitat zu Kiel (1997)
  • Salivary and Cell Surface Glycoprotein Receptors for Oral Bacterial Lectins as Mediators of Host-Microbial Interactions, ERGOB Meeting 1996 (1996)
  • Nomenklatur, Atiologie und Pthogenese der marginalen Parodontopathien, 3. Zliner Zhnarztetag (1996)
  • Lektin-vermittelte Interaktion von oralen Bakterien mit granulozytaren Glykoproteinrezeptoren, Mikroibiologisch-Immunologisches Kolloquium, Hygiene-Institut der Universitat Gottingen (1995)
  • Bacterial Lectin-Receptors on Human Granulocytes, The Procter & Gamble Company, Worldwide Clinical Investigation - Oral (1994)
  • Polymorphonuclear Leukocyte Receptors for Oral Bacterial Lectins, Research Center in Oral Biology, University of Pennsylvania (1994)
  • Leukosialin: A Granulocyte Receptor for Streptococcal and Actinomyces Lectins, NIH-Interinstitute Glycobiology Interest Group, National Institutes of Health (1994)
  • Der Interleukin-2 Rezeptor, Klinik fur Zahnarztliche Prothetik, Universitat Bern (1991)
  • Regulation of IL-2 Receptor Expression on Differentiating Macrophages, Forsyth Dental Center (1991)
  • Regulation von Interleukin-2 Receptoren vahrend der Makrophagen-Differnzierung, Mikrobiologisch-Immunologisches Kolloquium, Hygiene-Institut der Universitat Gottingen (1991)
  • The Interleukin-2 Receptor on Haematopoietic Cells, Laboratory of Immunology, National Institute of Dental Research, NIH (1991)
  • Der Interleukin-2 Rezeptor und seine Rolle im Prozeb der Differenzierung myeloider Zellen, Poliklinik fur Zahnarztliche Chirurgie U. Parodontologie, Eberhard-Karls-Universitat Tubingen (1989)
Service Activiites:
  • School of Dental Medicine Student Research and Honors Committee; Chair (2015)
  • School of Dental Medicine Graduate Committee, Admissions, Oral Biology; Member (2009-2015)
  • School of Dental Medicine Student Research and Honors Committee; Co-Chair (2008-2015)
  • School of Dental Medicine Admissions Committee; Member (2007-2013)
  • Past President, IADR Salivary Research Group; Past President (2014-2015)

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  • Organizer and Chair: IADR Salivary Research Group Business Meeting, Cape Town, SA; Chair (2014-2014)
  • IADR Keynote Address; Salivary Gland Organogenesis, Engineering and Evolution; Chair (2014-2014)
  • IADR Symposium: Current Updates on Dry Mouth Diagnosis and Management: Where Are We?; Chair (2014-2014)
  • Organizer: IADR Symposium "Novel Approaches to Functional Regeneration of the Salivary Gland"; Coordinator (2013-2013)
  • Resarch Panel, UB Pre-Health Symposium; Panel Member (2013-2013)
  • IADR Symposium: Novel Approaches to Functional Regeneration of the Salivary Gland; Chair (2013-2013)
  • IADR/AADR Salivary Research Group; President (2013-2014)
  • Research Panel, UB Prehealth Symposium; Panel Member (2013-2013)
  • AADR Saliva in Health and Disease; Chair (2012-2012)
  • IADR/AADR Salivary Research Group; Vice President (2012-2013)
  • AADR Oral Biology (Seq. #38); Chair (2010-2010)
  • AADR Fellowship Committee; Member (2010-2014)
  • AADR/IADR Salivary Research Group; Committee Member (2010-2012)
  • Organizer of the Department's Seminar Series in Oral Biology Seminar; Coordinator (2009-2012)
  • Salivary Research, Keynote Address and Normal Homeostasis; Co-Chair (2008-2008)
  • Saliva - Biomarkers / Structure and Function; Rochester Oral Biology Research Conference; Co-Chair (2008-2008)
  • Symposium "Saliva - Diagnostic Medium of the Future"; Annual meeting of the German Dental Association, November 22, Dusseldorf, Germany; Chair (2007-2008)
  • Study Group of Basic Sciences; AfG, DGZMK, Mainz, Germany; Chair (2006-2006)
  • Adherence/Adhesion (Seqq. #301.0); 83rd General Session and Exhibition of the International, American and Canadian Associations for Dental Research, Baltimore, MD; Chair (2005-2005)
  • Study Group of Basic Sciences; AfG, DGZMK, Mainz, Germany; Chair (2005-2005)
  • Editorial Board of the Journal of Dental Research; Editorial Board Member (2005-2007)
  • Committee for Therapeutical Drugs; Member (2005-2007)
  • Training for University Teachers in Pediatric Dentistry; Germany; Chair (2004-2004)
  • Gingival Overgrowth (Seq. #254); 81st General Session and Exhibition of the International Association for Dental Research, Goteborg, Sweden; Chair (2003-2003)
  • Caries Risk Management; ConsEuro, Munich, Germany; Chair (2003-2003)
  • Study Group of Basic Sciences; Scientific Program, AfG, DFZMK, Hannover, Germany; Chair (2002-2002)
  • 6th European Symposium on Saliva,; Egmond aan Zee, The Netherlands; Chair (2002-2002)
  • Mechanism of Secretion/Protein Expression (Seq. #45),; 80th General Session and Exhibition of the International Association for Dental Research, San Diego, CA; Chair (2002-2002)
  • Oral Biology of the Child, 8; Jahrestagung der Gesellschaft fur Kinderzahnheilkunde und primarprophyaxe (GKP) in der DGZMK; Chair (2001-2001)
  • Board of Examiners; Final exam for D.D.S. degree; Board Member (2001-2007)
  • Salivary Proteins/Molecules (Seq. #45); 77th General Session and Exhibition of the International Association for Dental Research, Vancouver, Canada; Chair (1999-1999)
  • Microbiology/Immunology I (Seq. #3); 3rd CED/NOF Joint Meeting, Berlin, Germany; Chair (1996-1996)
  • German Research Foundation (DFG); Two article reviews; External Reviewer (1995-2007)
  • Review Activities; Reviewer for the Following Scientific Journals: Clinical Oral Investigation Deutsche Zahnarztliche Zeitschrift Journal of Dental Research European Journal of Oral Sciences Archives of Oral Biology Oral Diseases Caries Research Anatomia Histologia Embryologia J. of Veterinary Medicine Proteomics Planta Medica-Natural Products and Medicinal Plant Research Journal of Pharmacological Sciences Oral Biosciences and Medicine Biomacromolecules Drug Discovery Today Immunological Investigations Journal of Anatomy Journal of Nanoscience and Nanotechnology Journal of Proteome Research; Reviewer (1995)