Ernesto DeNardin  PhD

Department of Oral Biology

Professor

Specialty/Research Focus

Oral Biology

Faculty Research Profile

 
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Education and Training:
  • Postdoctoral Fellow, Oral Biology, State University of New York at Buffalo (1986)
  • PhD, Immunology, Roswell Park Memorial Institute (SUNY at Buffalo) (1983)
  • MS, Natural Sciences, Roswell Park Memorial Institute (SUNY at Buffalo) (1978)
  • BS, Biology, Syracuse University (1976)
Employment:
  • Professor, Oral Biology, State University of New York at Buffalo (2002-present)
  • Professor, Microbiology and Immunology, State University of New York at Buffalo (2002-present)
  • Director, Monoclonal Antibodies and Immunoreagents Laboratory, Oral Biology, State University of New York at Buffalo (1983-present)
  • Associate Professor, Microbiology and Immunology, State University of New York at Buffalo (1996-2002)
  • Associate Professor, Oral Biology, State University of New York at Buffalo (1995-2002)
  • Assistant Professor, Microbiology and Immunology, State University of New York at Buffalo (1993-1996)
  • Assistant Professor, Oral Biology, State University of New York at Buffalo (1992-1995)
  • Senior Research Scientist, Oral Biology, State University of New York at Buffalo (1986-1992)
  • Post Doctoral Fellow, Oral Biology, State University of New York at Buffalo (1983-1986)
Awards and Honors:
  • Chancellor's Award for Excellence in Teaching (2011)
  • Richard A. Powell Award for Teaching Excellence (2010)
  • Charles S. Lipani Award for Exceptional Service, School of Dental Medicine, (2008)
  • Top 100 Federal Grantees, SUNY at Buffalo (2005)
  • Top 100 Federal Grantees, SUNY at Buffalo (2002)
  • Exceptional Scholar Program, Sustained Achievement Award, SUNY at Buffalo. (2002)
  • Edward H. Hatton International Competition: First Award Mentor (1995)

Research Expertise:
  • Research Expertise: Mammalian cell surface components and their functions; receptor-ligand interactions; role of leukocytes in host's defense; leukocyte-microbial/viral interactions; chemotactic mechanisms in disease; cell motility; transmembrane message transmission; gene cloning and recombinant DNA; site-directed mutagenesis; peptide synthesis and microsequencing. Relationship between chronic infections and systemic diseases. Genetic polymorphisms of disease.
Grants and Sponsored Research:
  • July 2001-July 2007
    Molecular aspects of neutrophil function in dental disease (2001-2006).
    NIH
    Role: Principal Investigator
    $900,000.00
  • January 1997-December 2000
    Molecular aspects of neutrophil function in dental disease (1997-2000).
    NIH
    Role: Principal Investigator
    $544,186.00
  • January 1992-December 1993
    Progression of the risk markers associated with juvenile periodontitis in the USA Subcontract: Studies of neutrophil function in localized juvenile periodontitis.
    NIH
    Role: Principal Investigator
    $66,040.00
  • January 1992-December 1996
    Molecular aspects of neutrophil function in dental disease (1992-1996).
    NIH
    Role: Principal Investigator
    $447,000.00
  • January 1990-December 1990
    PCR amplification and characterization of the FMLP receptor DNA from normal and chemotactically depressed LJP patients.
    Biomedical Research Support Grant
    Role: Principal Investigator
    $6,500.00
  • January 1989-December 1989
    Gene cloning of the human formyl peptide (FMLP) receptor.
    Biomedical Research Support Grant
    Role: Principal Investigator
    $7,000.00
  • January 1987-December 1992
    Neutrophil function in dental disease (1987-1992).
    NIH
    Role: Principal Investigator
    $375,000.00
  • January 1986-December 1989
    Neutrophil function in dental disease (1986-1989).
    NIH
    Role: Co-Investigator
    $108,000.00

Journal Articles:
  • Andriankaja O, Sreenivasa R, Dunford R, De Nardin E. Association between metabolic syndrome and periodontal disease. Australian Dent. J. 2010; 55.
  • Sahingur SE, Xia XJ, Gunsolley J, Schenkein HA, Genco RJ De Nardin E. Single nucleotide polymorphisms of pattern recognition receptors and chronic periodontitis J. Periodontal Res.. 2010; 46.
  • Tobias K. Boehm, Hakimuddin T.Sojar and Ernesto Denardin. Concentration-dependent effect of fibrinogen on IgG-specific antigen binding and phagocytosis Cellular immunology. 2010; 263.
  • Aguirre A, Hatton MN, DeNardin E, Sialadenitis E. Sialadenitis British Medical Journal. 2009.
  • DeNardin E. Genetic polymorphisms and immune responses. Immunol Invest. 2009; 38(3-4).
  • Morozumi T, Sharma A, DeNardin E. The functional effects of the -455G/A polymorphism on the IL-6-induced expression of the beta-fibrinogen gene may be due to linkage disequilibrium with other functional polymorphisms. Immunol Invest. 2009; 38(3-4).
  • Boehm TK, DeNardin E. Fibrinogen binds IgG antibody and enhances IgG-mediated phagocytosis Human Antibodies. 2008; 17(3-4).
  • Morotsumi T, Sharma A, DeNardin E. The effect of gene polymorphisms on the interleukin 6-induced transcriptional activity the β-fibrinogen promoter region Thrombosis Research. 2008.
  • Sahingur SE, Boehm TK, Sojar HT, Sharma A, DeNardin E. Fibrinogen-neutrophil interactions in response to fMLP and Porphyromonas gingivalis fimbrial peptides. Immunol Invest. 2006; 35(1).
  • Hajishengallis G, Sojar H, Genco R, DeNardin E. Intracellular signaling and cytokine induction upon interactions of Porphyromonas gingivalis fimbriae with pattern-recognition receptors. Immunol Invest. 2004; 33(2).
  • Yamamoto K, Kobayashi T, Grossi S, Ho AW, Genco RJ, Yoshie H, De Nardin E, DeNardin E. Association of Fcgamma receptor IIa genotype with chronic periodontitis in Caucasians. J Periodontol. 2004; 75(4).
  • Sahingur SE, Genco RJ, Sharma A, DeNardin E. Association of increased levels of Fibrinogen and the -455G/A Fibrinogen Gene Polymorphism with Chronic Periodontitis J Periodontol. 2003; 74.
  • Glurich I, Grossi S, Albini B, Ho A, Shah R, Zeid M, Baumann H, Genco RJ, DeNardin E. Systemic Inflammation in Cardiovascular and Periodontal Disease: Comparative Study Clinical and Diagnostic Laboratory Immunology. 2002; 9(2).
  • Hajishengallis G, Martin M, Sojar H, Sharma A, Schifferle R, DeNardin E, Russell MW, Genco RJ. Dependence of bacterial protein adhesin on toll-like receptors and proinflammatory cytokine induction Clin Diagn Lab Immunol. 2002; 9(2).
  • DeNardin E. The role of inflammatory and immunological mediators in periodontitis and cardiovascular disease. Ann Periodontol. 2001; 6(1).
  • Genco RJ, Glurich I, Haraszthy V, Zambon J, DeNardin E. Overview of risk factors for periodontal disease and implications for diabetes and cardiovascular disease. Compend Contin Educ Dent. 2001; 22(2 Spe).
  • Noack B, DeNardin E, Genco RJ, Hoffmann T. Systemische Akutphaseantwort bei Parodontitis marginalis Deutsche Zahnarztliche Zeitschrift. 2001; 56.
  • Noack B, Genco RJ, Trevisan M, Grossi S, Zambon JJ, DeNardin E. Periodontal Infections Contribute to Elevated Systemic C-Reactive Protein Level J Periodontol. 2001; 72(9).
  • Guo M, Han Y, Sharma A, DeNardin E. Identification and Characterization of Human Immunoglobulin G Fc Receptors of Fusobacterium nucleatum Oral Microbiol Immunol. 2000; 15.
  • Guo M, Reynolds M, Stinson M, DeNardin E. Isolation and characterization of a human neutrophil aggregation-defective mutant of Fusobacterium nucleatum. FEMS Immunol Med Microbiol. 2000; 27.
  • Katancik JA, Sharma A, de Nardin E, DeNardin E. Interleukin 8, neutrophil-activating peptide-2 and GRO-alpha bind to and elicit cell activation via specific and different amino acid residues of CXCR2. Cytokine. 2000; 12(10).
  • Lorton D, Schaller J, Lala A, DeNardin E. Chemotactic-like receptors and Ab peptide induced responses in Alzheimer‘s disease. Neurobiol Aging. 2000; 21.
  • Miura Y, Tohyama Y, Hishita T, Lala A, DeNardin E, Yamamura H, Uchiyama T, Tohyama K. Pyk2 and Syk participate in functional activation of granulocytic HL-60 cells in a different manner. Blood. 2000; 96.
  • Glurich I, Sojar H, DeNardin A, Haraszthy V, Grossi S, Ho A, Albin B, Reynold H, Shah R, Zeid M, Genco RJ, DeNardin E. Periodontitis atherosclerosis and the immune response:possible immunopathologic links 1999.
  • Gwinn M, Sharma A, DeNardin E. Single Nucleotide Polymorphisms of the N-Formyl Peptide Receptor in Localized Juvenile Periodontitis J Periodontol. 1999; 70.
  • Lala A, Gwinn A, DeNardin E. Human formyl peptide receptor function: Role of polar residues conserved and non-conserved. Eur J Biochem. 1999; 264.
  • Nguyen LT, Ramanathan M, Munschauer F, Brownscheidle C, Krantz S, Umhauer M, Miller C, DeNardin E, Jacobs LD. Flow cytometric analysis of in vitro proinflammatory cytokine secretion in peripheral blood from multiple sclerosis patients. J Clin Immunol. 1999; 19(3).
  • Dentino A, Periathamby AR, DeNardin E. Subtle differences between human and rabbit neutrophil receptors shown by the secretagogue activity of constrained formyl peptides. Arch Biochem Biophys. 1997; 337.
  • Katancik JA, Sharma A, Radel SJ, DeNardin E. Mapping of the Extracellular Binding Region of the Human Interleukin-8 Receptor Biochem Biophys Res Commun. 1997; 232.
  • Lala A, Sojar HT, DeNardin E. Expression, purification and immunochemical characterization of recombinant human FMLP receptor. Biochem Pharmacol. 1997; 54.
  • Venkatraman JT, Rowland JA, Denardin E, Horvath PJ, Pendergast D. Influence of the level of dietary lipid intake and maximal exercise on the immune status in runners. Med Sci Sports Exerc. 1997; 29(3).
  • DeNardin E. The molecular basis for neutrophil dysfunction in early onset periodontal diseases. J Periodontol. 1996; 67.
  • Gonzalez Y, DeNardin A, Grossi S, Machtei EE, DeNardin E, Genco RJ. Serum Cotinine Levels, Smoking, and Periodontal Attachment Loss J Dent Res. 1996; 75(2).
  • Kopman JA, Genco R, Grossi SG, Dunford RG, DeNardin E. Relationship of Salivary Cortisol to Psychosocial Risk Indicators for Periodontal Disease J Dent Res. 1996; 75.
  • Lala A, Sojar H, DeNardin E. A quantitative approach for detection and characterization of formyl peptide receptor in solution using a photoaffinity ligand Pept Res. 1996; 9.
  • Zheng WP, Kiura K, Milisauskas VK, DeNardin E, Nakamura I. Murine NK cell allospecificity-1 is defined by inhibitory ligands. J Immunol. 1996; 156(12).
  • Basiri H, Kiura K, DeNardin E, Nakamura I. Allospecificities of B6D2F1 hybrid NK cell subsets defined by Ly-49A expression. J Immunol. 1995; 155.
  • Brant E, Sojar HT, Sharma A, Bedi G, Genco RJ, DeNardin E. Identification of linear antigenic sites on the Porphyromonas gingivalis 43 kDa fimbrillin subunit. Oral Microbiol Immunol. 1995; 10.
  • Andreana S, De Nardin E., Giardino L., Pecora G. Immunoglobulin A and Oral Cavity Rivista Italiana di Stomatologia. 1994; 133.
  • Andreana S, DeNardin E, Giardino L, Pecora G. Le Immunoglobuline A ed il Cavo Orale Riv Ital Stomatol. 1994.
  • Brant EE, Sojar H, Sharma A, Bedi GS, Genco RJ, DeNardin E. Identification of Linear Antigenic Sites on the Porphyromonas gingivalis 43-kDA Fimbrillin Subunit Oral Microbiol Immunol. 1994; 9.
  • Lala A, Amano A, Sojar H, Radel SJ, DeNardin E. Porphyromonas gingivalis trypsin-like protease: a possible natural ligand for the neutrophil formyl peptide receptor. Biochem Biophys Res Comm. 1994; 3.
  • Radel SJ, Genco RJ, De Nardin E. Structural and functional characterization of the human formyl peptide receptor ligand binding region. Infect Immun. 1994; 62.
  • Lala A, Sharma A, Sojar H, Radel RJ, Genco RJ, DeNardin E. Recombinant Expression and Partial Characterization of the Human Formyl Peptide Receptor Biochimica et Biophysica Acta. 1993; 1178.
  • Lala A, Sharma A, Sojar H, Radel SJ, Genco RJ, DeNardin E. Recombinant Expression and Partial Characterization of the Human Formyl Peptide Receptor Biochimica et Biophysica Acta. 1993.
  • DeNardin E, Radel SJ, Lewis N, Genco RJ, Hammarskjold M. Identification of a Gene Encoding for the Human Formyl Peptide Receptor Biochemistry International. 1992; 26(3).
  • Gillespie J, DeNardin E, Radel SJ, Kuracina J, Smutko J, Zambon J. Production of an extracellular toxin by the oral pathogen Wolinella recta. Microbial Pathogenesis. 1992; 12.
  • DeNardin E. Role of neutrophils in periodontal disease Prog Odontoiatr. 1991; 4(3).
  • DeNardin E. Il ruolo dei neutrofili nelle malattie parodontali. Il Progresso Odontoiatrico. 1991; IV(3).
  • DeNardin E, Genco RJ. Immunochemical Characterization of the Formyl Peptide Receptor Moieties on Human Neutrophils Hybridoma. 1991; 10(1).
  • DeNardin E, Radel SJ, Genco RJ. Isolation and Partial Characterization of the Formyl Peptide Receptor Components on Human Neutrophils Biochemical and Biophysical Research Communications. 1991; 174(1).
  • Radel S, Genco RJ, DeNardin E. Localization of Ligand Binding Regions of the Human Formyl Peptide Receptor Biochem International. 1991; 25(4).
  • DeNardin E, DeLuca C, Levine MJ, Genco RJ. Antibodies directed to the chemotactic factor receptor detect differences between chemotactically normal and defective neutrophils from LJP patients. J Periodontol. 1990; 61(10).
  • Zambon, J.J., T. Umemoto, E. De Nardin, F. Nakazawa, L.A. Christersson, R.J. Genco. Actinobacillus actinomycetemcomitans in the pathogenesis of human periodontal disease Advances in Dental Res. 1988; 2.
  • Glurick I, Haraszthy V, Zambon JJ, DeNardin E. An IgM pan-T monoclonal antibody that blocks E-rosette formation. Hybridoma. 1985; 4.
See All (55 Total) >

Abstracts:
  • Sahingur SE, Gunsolley J, DeNardin E, Genco R, Schenkein HA. Single Nucleotide Polymorphisms of Toll Like Receptors and Chronic Periodontitis.. J Dent Res. 2008.
  • DeNardin E. Fimbrial Peptides and Fibrinogen Binding in Neutrophils. Inflammation Research Symposium at UB, State University of New York at Buffalo. J Dent Res. 2006.
  • Andriankaja, OM, Dunford, R, DeNardin E. The Association Between Metabolic Syndrome and Periodontal Disease. J Dent Res. 2006.
  • Andriankaja, OM, DeNardin E, Dunford, R, Dorn, J, Trevisan, M. The Association Between Metabolic Syndrome and Periodontal Disease. 2006 Congress of Epidemiology. J Dent Res. 2006.
  • Boehm, T, Sahingur, E, DeNardin E. Fimbrial Peptides Enhance Fibrinogen Binding to Neutrophils and HL60 Cells. AADR Meeting, Orlando, Florida. J Dent Res. 2006.
  • Hajishengallis G, Sojar H, Sharma A, Martin M, DeNardin E, Genco RJ. TLR-4 Dependent Upregulation of Costimulatory Molecules in Macrophages by P. gingivalis FimA. IADR Meeting, San Diego, CA. J Dent Res. 2002.
  • Sojar H, Sharma A, Martin, M., Schifferle R, DeNardin E, Genco RJ. Host Regulatory Interactions Between P. gingivalis Fimbriae and LPS.. J Dent Res. 2001; 80SI(578).
  • DeNardin E. Molecular Polymorphisms in Genes Related to Inflammatory and Immune Molecules. IADR Meeting in Chiba, Japan. J Dent Res. 2001.
  • Hajishengallis, G, Sojar H, Sharma A, Martin, M, Schifferle R, DeNardin E, Genco RJ. Host Regulatory Interactions Between P. gingivalis Fimbriae and LPS. IADR Meeting in Chiba, Japan. J Dent Res. 2001.
  • Sojar H, Han Y, Hamada N, Sharma A, DeNardin E. Role of the Amino Terminal Region of Porphyromonas gingivalis Fimbriae in Adherence to Epithelial Cells.. J Dent Res. 1999; 78.
  • Glurich, I, Bronson, P, Grossi S, Ho, A, Baumann, H, Genco RJ, DeNardin E. Ceruloplasmin, a1-Acid Glycoprotein, and a1-Chymotrypsin Levels in Periodontal and Cardiovascular Disease. J Dent Res. 1999; 78.
  • Albandar, JM, DeNardin E. Serum IgG Levels to P. gingivalis in Early-Onset Periodontitis Individuals. J Dent Res. 1999; 78.
  • Guo, M, Han, YP, Sharma A, DeNardin E. Characterization of the Human IgG Fc Receptors of Fusobacterium nucleatum. J Dent Res. 1999; 78.
  • Lala, A, DeNardin E. Role of Charged Residues of Human Neutrophils FMLP Receptor. J Dent Res. 1999; 78.
  • Lambert, B, Lala, A, DeNardin E. Role of Arginine and Lysine in Formyl Peptide Receptor Function. J Dent Res. 1999; 78.
  • Glurich I, Sojar H, Albini B, Ho A, Zeid M, Shah R, Wick G, Genco RJ, DeNardin E. Does immune response to heat shock proteins in periodontal disease influence atherogenesis?. Infect Dis Obstet Gynecol. 1999.
  • Katancik, JA, Sharma A, DeNardin E. Point Mutagenesis Studies of the Human Neutrophil CXC Chemokine Receptor-2. J Dent Res. 1999; 78.
  • Gwinn, MR, Lewins, SN, Sharma A, DeNardin E. Sequence Analysis of the Interleukin-8 (IL-8) Receptor in Localized Juvenile Periodontitis. J Dent Res. 1999; 78.
  • Sahingur, SE, Gwinn, MR, Sharma A, DeNardin E. Restriction Fragment Length Polymorphisms in the Promoter Region of the B-Fibrinogen Gene in Adult Periodontitis Patients and Healthy Subjects. J Dent Res. 1999; 78.
  • Gwinn M, Sharma A, DeNardin E. Sequence Analysis of Chemotactic Receptor DNA in Localized Juvenile Periodontitis. IADR Meeting in Nice, France. J Dent Res. 1998.
  • Katancik, JA, Sharma A, DeNardin E. Point Mutagenesis Studies of the Human Interleukin-8 Type B Receptor. AADR Minneapolis Meeting. J Dent Res. 1998.
  • Gwinn M, Sharma A, DeNardin E. Sequence Analysis of FMLP Receptor DNA in LJP. J Dent Res. 1998.
  • Glurich, I, Grossi S, Ho, A, Baumann, H, Genco RJ, DeNardin E. Inflammation, Peridontal Disease and Atherogenesis: A Possible Link. IADR Meeting in Nice, France. J Dent Res. 1998.
  • Glurich, I, Genco RJ, Grossi S, DeNardin, A, Albini, B, Wick, G, Dunford, R, Ho, A, DeNardin E. Immune Response to Periodontal Pathogens and Cardiovascular Disease: A Possible Link. IADR Meeting in France, Nice. J Dent Res. 1998.
  • Gwinn, M, Sharma A, DeNardin E. Single Strand Conformation Polymorphism Analysis of FMLP Receptor-Encoding DNA. J Dent Res. 1997; 76.
  • Lala, A, Carpio, L, DeNardin E. Role of Aspartete in Cellular Activity of Human Neutrophil FMLP Receptor. J Dent Res. 1997; 76.
  • Lala, A, DeNardin E. Role of Polar Amino Acids in Ligand Binding Interaction of Human Neutrophil FMLP Receptor. J Dent Res. 1996; 75.
  • Gwinn, M, Sharma A, DeNardin E. Single Strand Conformation Polymorphism Analysis of the FMLP Receptor. J Dent Res. 1996; 75.
  • Kopman JA, Genco R, Grossi SG, Dunford RG, DeNardin E. Relationship of Salivary Cortisol to Psychosocial Risk Indicators for Periodontal Disease. J Dent Res. 1996; 75.
  • Venkatraman, JT, Rowland, JA, DeNardin E, Hoevath, PJ, Pendergast, DR. Influence of Levels of Dietary Lipids End Exercise on Immune Status in Athletes. Federation of the American Societies for Experimental Biology. 1996.
  • Gwinn, M, Sharma A, DeNardin E. Single Strand Conformation Polymorphism Analysis of FMLP Receptor DNA. 22nd Annual Maine Biological and Medical Sciences Symposium. The University of Maine at Orono. 1996.
  • Lala, A, Sojar H, Genco RJ, DeNardin E. Purification and Characterization of Recombinant Human FMLP Receptor. J Dent Res. 1995; 74.
  • Lala A, Sojar H, Genco RJ, DeNardin E. Purification and characterization of recombinant human FMLP receptor.. J Dent Res. 1994.
  • Zheng, WP, DeNardin E, Basiri, H, Nakamura, I. Expression of the Hh-1b Phenotype in Dd-Negative Variants of H-2b/d and H-2d Hemopoietic Tumor Cells. Federation of the American Societies for Experimental Biology, Anaheim, CA. 1994.
  • Basiri, H, Milisauskas, V, DeNardin E, Nakamura, I. Hh-1-Specific Recognition of Allogeneic Normal and Leukemic Target Cells In vitro by IL-2-Activated Mouse NK Cells. Federation of the American Societies for Experimental Biology, Anaheim, CA. 1994.
  • Radel, SJ, DeNardin E. Characterization of the Ligand Binding Region in the Human Formyl Peptide Receptor. Federation of the American Societies for Experimental Biology, Anaheim, CA. 1994.
  • Kirkham, C, Surface, JM, DeNardin E, Lesse, AJ, Murphy, TF. Epitope Structure of CD, the Major Heat-Modifiable Outer Membrane Protein on Moraxella (Btanhamella) Catarrhalis. The American Society for Microbiology, Las Vegas, Nevada. 1994.
  • Surface, JM, Sethi, S, DeNardin E, Murphy, T. Antigernic Heterogeneity of Outer Membrane Protein B of Moraxella (branhamella) catarrhalis. The American Society for Microbiology, Las Vegas, Nevada. 1994.
  • Lala, A, Sharma A, Sojar H, Radel, SJ, Genco RJ, DeNardin E. Cloning and Expression of FMLP Receptor in E. coli. International Association for Dental Research, Chicago, IL. J Dent Res. 1993.
  • DeNardin E, Radel, SJ, DeNardin, AM, Genco RJ. Characterization of the Ligand Binding Regions of the Human IL-8 Receptor. International Association for Dental Research, Chicago, IL. J Dent Res. 1993.
  • Katancik, J, DeNardin, AM, Genco RJ, DeNardin E. The Interaction of P. gingivalis with Human Peripheral Neutrophils. International Association for Dental Research, Chicago, IL. J Dent Res. 1993.
  • Radel, SJ, Genco RJ, DeNardin E. Determination of the Ligand Binding Region of the Human Foryml Peptide Receptor. Federation of the American Societies for Experimental Biology, New Orleans, Louisiana. 1993.
  • Andreana, S, Barboni, MG, DeNardin E. Differences in Microflora from Fistula and Canal in Endodontic Infection. International Federation of Endodontic Associations, Paris, France. 1992.
  • Radel, SJ, DeNardin E, Genco RJ. Functional Mapping of the Formyl Peptide Receptor Using Synthetic Peptides. J Dent Res. 1992; 71.
  • Radel SJ, Genco RJ, DeNardin E. Localization of Ligand Binding Regions of the Human Formyl Peptide Receptor. 1992.
  • Andreana S, Pecora, G, Barboni, MG, Maleandri, M, Fabi, M, Andreana, G, DeNardin E. Serum Antibodies Studies on Patients with Treatment Resistant Endodontic Lesions. J Dent Res. 1992; 18(4).
  • Barboni MG, Andreana S, DeNardin E. Differences in Microflora from Fistula and Canal in Endodontic Infections. IFEA. 1992.
  • Radel, SJ, Kolluri, RV, Firulli, AB, DeNardin E, Kinninburgh, AJ, Genco RJ. Oligonucleotide Probes to Identify Formyl Peptide Receptor DNA. J Dent Res. 1991; 70.
  • DeNardin E, Radel, S, Genco RJ. Biochemical and Functional Characterization of the Formyl Peptide Receptor on Human Neutrophils. International Association for Dental Research, Acapulco, Mexico. J Dent Res. 1991.
  • Gillespie, MJ, Smutko, JS, Kuracina, J, DeNardin E, Radel, S, Zambon JJ. Studies of an Extracellular Protein Toxin from Wolinella recta. J Dent Res. 1991.
  • Gillespie, J, Smutko, J, Kuracina, J, DeNardin E, Radel, S, Zambon JJ. Studies of an Extracellular Protein Toxin from Wolinella recta. J Dent Res. 1991; 70(1919).
  • Gillespie MJ, DeNardin E, Cho M, Zambon JJ. Isolation and Characterization of Fimbrial Proteins from A. actinomycetemcomitans. J Dent Res. 1990.
  • Sunday, GJ, Gillespie, MJ, Kuracina, J, Smutko, JS, DeNardin E, Radel, S, Zambon JJ. Detection of Leukotoxin Gene Sequences and Cytotoxicity in Oral Bacteria. International Association for Dental Research, Cincinnati, OH. J Dent Res. 1990.
  • Gillespie, MJ, Kuracina, J, DeNardin E, Radel, S, Zambon JJ. Evidence of an Extracellular Leukotoxic Activity in Wolinella recta. The American Society for Microbiology, Anaheim, CA. 1990.
  • DeNardin E, Levine MJ, DeLuca C, Genco RJ. Biochemical and structural characteristics of the formyl peptide receptor on human neutrophils.. J Dent Res. 1988; 67.
  • DeNardin E, DeLuca C, Levine MJ, Genco RJ. Differences in the formyl peptide receptor between chemotactically normal and defective neutrophils.. J Dent Res. 1987.
  • DeNardin E, DeLuca C, Levine MJ, Genco RJ. Alterations of the FMLP receptor on chemotactically defective neutrophils.. Fed Amer Soc Exp Biol. 1987.
  • Miyasaki, K, Brunetti, A, DeNardin E, Wilson, M, Genco RJ. Probing the Subunit Structure of Human Neutrophil Myeloperoxidase Using Monoclonal Antibodies. American Association for Dental Research, Washington, DC. J Dent Res. 1986.
  • DeNardin E, DeLuca C, Levine MJ, Genco RJ. Differences in the formyl peptide receptor between chemotactically normal and defective human neutrophils as defined by monoclonal antibodies.. Fed Amer Soc Exp Biol. 1986.
  • DeNardin E, Sobel, J, Zambon JJ, Neiders M, Evans R, Genco RJ. Serological Characterization of Actinobacillus actinomycetemcomitans Using Monoclonal Antibodies. International Association for Dental Research, Las Vegas, Nevada. J Dent Res. 1985.
  • DeNardin E, Sobel J, Zambon JJ, Neiders M, Evans R, Genco RJ. Serological Characterization of Actinobacillus actinomycetemcomitans Using Monoclonal Antibodies. FASEB J. 1985.
  • DeNardin E, Sprowl, C, Evans R, Stinson, M, Genco RJ. Novel Surface Antigen of Streptococcus mutans Defined by Monoclonal Antibodies. International Association for Dental Research, Las Vegas, Nevada. J Dent Res. 1985.
  • DeNardin E, Sobel J, Neiders M, Evans RT, Genco RJ. Serologic characterization of Actinobacillus actinomycetemcomitans. J Dent Res. 1985; 64.
  • DeNardin E, Sobel, J, Zambon JJ, Neiders M, Evans R, Genco RJ. Serologic Characteristics of Actinobacillus actinomycetemcomitans using Monoclonal Antibodies. Fed Proc. 1985; 44(679).
  • DeNardin E, Tanigaki, N. The E-Rosette Receptor as Defined by a Novel Monoclonal Antibody. American Society for Microbiology Meeting, SUNY at Buffalo, Buffalo, NY. 1983.
  • DeNardin E, Tanigaki, N. A Murine Monoclonal Antibody that May Recognize a Leukemia/Lymphoma Associated Antigen. The Fifth Lake Ontario Immunology Conference, SUNY at Buffalo, Buffalo, NY. 1983.
  • DeNardin E, Tanigaki, N. An IgM pan=T Monoclonal Antibody that Blocks E-rosette Formation. The Fourth Lake Ontario Immunology Conference, University of Rochester, Rochester, NY. 1982.
  • DeNardin E, Tanigaki, N. Monoclonal Antibodies and Hybridoma Technology: A Review. The Third Lake Ontario Immunology Conference, Syracuse University, Syracuse, NY. 1981.
  • DeNardin E, Levine M, Genco RJ, DeLuca C. Identification of a formyl peptide receptor epitope associated with depressed chemotaxis in localized juvenile periodontitis.. J Dent Res. 1900.
See All (69 Total) >
Books and Book Chapters:
  • Rittenhouse-Olson K, DeNardin E. Contemporary Clinical Immunology and Serology. Contemporary Clinical Immunology and Serology. 2013.
  • De Nardin E. Neutrophil receptors: N-formyl-methionyl-l-leucyl-1-phenylalanine and Interleukin-8.. Molecular Pathogenesis of Periodontal Disease. 1994.
  • Sorge KF, Potts TV, De Nardin E. Application of PCR to oral diagnostic.. PCR-Based Diagnostics. 1993.
  • Genco RJ, Wilson M, De Nardin E. Periodontal complications of neutrophil abnormalities.. Contemporary Periodontics. 1989.
Professional Memberships:
  • Environmental Health Sciences Graduate Group - Toxicology Research Center (1993)
  • The National Science Foundation Young Scholars Program in Biological Sciences. A program designed to introduce outstanding high school students to the basic sciences. (1989-1995)
  • The International Association for Dental Research (1900)
  • The Ernest Witebsky Center for Immunology (1900)
Presentations:
  • Chemotactic receptors, and neutrophil function., Invited Speaker, University of Dresden (1999)
  • The relationship between periodontal infections and cardiovascular disease., Invited Speaker, University of Dresden (1999)
  • The molecular basis for neutrophil dysfunction in early onset periodontal diseases., Workshop on early onset periodontitis, University of Texas (1995)
  • Training modalities in basic research for students of dentistry., Invited Speaker, Universita della Sapienza (1994)
  • Organization of basic research in periodontology, Invited Speaker, Universita della Sapienza (1994)
  • The function of neutrophils in periodontal diseases., Invited Speaker, Universita della Sapienza (1994)
  • Surface receptors and neutrophil function., Invited Speaker, The University of Texas Health Science Center, (1993)
  • Neutrophil receptors: FMLP and IL-8., University of Buffalo School of Dental Medicine Centennial Symposium., University at Buffalo (1993)
  • Characterization of chemotactic receptors on human neutrophils., Invited Speaker, University at Buffalo (1993)
  • Molecular biology approaches to periodontal research, Invited Speaker, University of Erfurt (1993)
  • The role of neutrophils in periodontal diseases., Invited speaker, The University of Bologna (1991)
See All (11 Total) >
Service Activities:
  • School of Dental Medicine Student Progress and Promotions Committee; Member (2002)
  • School of Dental Medicine Curriculum Committee; Member (1998-2006)
  • School of Dental Medicine Executive Council; Member (1997-2001)
  • School of Dental Medicine Admissions Committee; Member (1993)

  • Buffalo Collegium of Immunology; President (2008)
  • Immunological Investigations; Associate Editor (2005)
  • Mini Medical School - School of Medicine, SUNY at Buffalo; Invited Participant (2002)
  • Mini Medical School - High School Science Enrichment Program; Invited Participant (2000)
  • The Ernest Witebsky Center for Immunology; Member (1999)
  • Buffalo Collegioum of Immunology; Member (1999)
  • Immunological Investigations; Reviewer (1995)
  • The International Association for Dental Research; Member (1984)
  • The American Association for Dental Research; Member (1984)
  • Community Service - SUNY at Buffalo, Dept. of Oral Biology.; Summer Research Program: for college and dental students (to supervise and train one or more students with various research projects). Oral Biology, SUNY at Buffalo.; Other (1983)
  • Roswell Park Cancer Institute-Summer Reserach Program; Summer Research Program: for college and dental students (to supervise and train one or more students with various research projects). Roswell Park Memorial Institute Summer Student Research Program.; Other (1980-1982)
  • The Journal of Dental Research; Reviewer
  • FEBS Letters; Reviewer
  • Biochemical Pharmacology; Reviewer
  • International Archives of Allergy and Immunology; Reviewer
  • Critical Reviews in Oral Biology and Medicine; Reviewer
  • Journal of Periodontology; Editorial Board Member
  • Annals of Periodontology; Editorial Board Member
  • International Journal of Oral Biology; Editorial Board Member
  • Journal of Clinical periodontology; Reviewer
See All (24 Total) >

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Contact Information

Foster Hall
Room 204
3435 Main Street
Buffalo, NY 14214
Phone: (716) 829-3998
Fax: (716) 829-3942
Email: denardin@buffalo.edu


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