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PubMed Central, ED Figure 10.: Nature. 2015 Oct 1; 526(7571): 75–81. doi:  10.1038/nature15394
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Nature. Author manuscript; available in PMC 2016 Apr 1.
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Nature. 2015 Oct 1; 526(7571): 75–81.
doi:  10.1038/nature15394

ED Figure 10.

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Examples for five classifications of inversions verified using PacBio and Minion reads: Simple Inversion (A), inv-dup (B), inv-del (C), MultiDel with Inv (here abbreviated as inv-2dels) (D) and complex (E). (F) Several further examples of inverted duplications (inv-dup), the most common form of inversion-associated SV identified in the phase 3 release set. The figure is depicting DNA sequence alignment dotplots (same arrangement as in Figure 3), with the Y-axis referring to PacBio DNA single molecule sequencing reads and the X-axis referring to the reference genome assembly (hg19). Inverted sequences are highlighted in red. Sequence analysis suggests that these inverted duplications are not typically associated with retrotransposition.

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