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PubMed Central, Figure 5: Sci Rep. 2016; 6: 31791. Published online 2016 Aug 25. doi:  10.1038/srep31791
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Published online 2016 Aug 25. doi:  10.1038/srep31791

Figure 5

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The adaptive evolution of MUC7 in mammals.

The upper-left panel shows the normalized ratio of nonsynonymous to synonymous variation for each functional segment of MUC7. The upper-right panel shows the overall nucleotide-level conservation for the same functional segments. The protein alignments of the signal peptide and the histatin-like domain that underlie these graphs are shown at the bottom. We did not include the PTS-repeat region in this analysis because copy number changes and sequence similarity introduce major alignment problems. P-values were calculated using a one-tailed Wilcoxon rank-sum test.

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