University at Buffalo - The State University of New York
Skip to Content
Comparative Evaluation of Corneal Endothelium in Patients with Diabetes Undergoing Phacoemulsification. - PubMed - NCBI
Format

Send to

Choose Destination
See comment in PubMed Commons below
Middle East Afr J Ophthalmol. 2017 Apr-Jun;24(2):74-80. doi: 10.4103/meajo.MEAJO_242_15.

Comparative Evaluation of Corneal Endothelium in Patients with Diabetes Undergoing Phacoemulsification.

Author information

1
Department of Ophthalmology, UCMS and GTB Hospital, New Delhi, India.

Abstract

PURPOSE:

The purpose of this study is to determine if phacoemulsification with posterior chamber foldable intraocular lens implantation has a greater impact on the corneal endothelium of type 2 diabetic patients as compared to nondiabetic controls.

MATERIALS AND METHODS:

This study compared the corneal endothelial status in sixty patients with diabetes with good glycemic control and sixty nondiabetic controls before and after (1 week, 1 month, 2 month, and 3 month) uneventful phacoemulsification. Central corneal endothelial cell density, percentage hexagonality, and coefficient of variation were measured using a noncontact specular microscope. Central corneal thickness was taken as a surrogate marker for endothelium functional status.

RESULTS:

Data were age and sex matched. Patients with diabetes showed significantly higher loss in endothelial cell count as compared to nondiabetic controls. Furthermore, the patients with diabetes showed a slower recovery trend in the endothelial healing response as evidenced by lower change in the coefficient of variation. Significant correlation was found between energy used and change in endothelial count as well as coefficient of variation in nondiabetics only.

CONCLUSION:

In spite of good glycemic control, patients with diabetes have significantly more endothelial damage in comparison to nondiabetic controls with similar nuclear grading and phaco energy used. This warrants a more careful use of phaco energy in patient with diabetes.

KEYWORDS:

Corneal endothelium; diabetic; phacoemulsification

PMID:
28936050
PMCID:
PMC5598306
DOI:
10.4103/meajo.MEAJO_242_15
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
    Loading ...
    Support Center