Pathologic classification of rhabdomyosarcomas and correlations with molecular studies.

DM ParhamĀ - Modern Pathology, 2001 -
Abstract Rhabdomyosarcoma, the most common soft-tissue malignancy of childhood and
adolescence, comprises a group of differing pathobiologic entities linked by their common
propensity for formation of neoplastic skeletal muscle, a feature that results from biological
forces related to aberrant transcription signals and the resultant production of myogenic
proteins. At a molecular level, however, rhabdomyosarcomas form a heterogeneous ...