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The Clinical Proteomic Technologies for Cancer | Details for synuclein, gamma (breast cancer-specific protein 1) Peptide 1

synuclein, gamma (breast cancer-specific protein 1) Peptide 1


Background

Catalog Number:

CPTC-SNCG-3

Target Antigen:

synuclein, gamma (breast cancer-specific protein 1) Peptide 1

Isotype:

IgG

Species:

Rabbit Monoclonal Antibody

Last Updated:

04/06/2015

Antigen Recognition(s):

Purchase
Characterization Data [Compare Characterization Data]
  Western Blot
Click to enlarge image Western Blot using CPTC-SNCG-3 as primary Ab against full-length recombinant Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and the SNCG-3 Ab as positive control (lane 3). Click image to enlarge

CPTC-SNCG-3 Western blot

Western Blot using CPTC-SNCG-3 as primary Ab against full-length recombinant Ag 10504 (lane 2). Also included are molecular wt. standards (lane 1) and the SNCG-3 Ab as positive control (lane 3).

  Cell Lysate Western Blot
Click to enlarge image Western Blot using CPTC-SNCG-3 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1). Click image to enlarge

CPTC-SNCG-3 NCI60 Western blot

Western Blot using CPTC-SNCG-3 as primary Ab against lysates from six breast cancer cell lines from the NCI60 cell line collection (lanes 2-7). Also included are molecular wt. standards (lane 1).

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 peptide ELISA

Indirect ELISA (ie, binding of Antibody to biotinylated peptide coated on a NeutrAvidin plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

  Indirect ELISA
Click to enlarge image Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding. Click image to enlarge

CPTC-SNCG-3 Indirect ELISA

Indirect ELISA (ie, binding of Antibody to full-length Antigen coated on plate). Note: B50% represents the concentration of Ab required to generate 50% of maximum binding.

Background

NCI Identification Number:

00040

Antigen Name:

synuclein, gamma (breast cancer-specific protein 1) Peptide 1

CPTC Name:

CPTC-SNCG Peptide 1

Keywords:

BCSG1; SR; Persyn; Breast Cancer-Specific Gene 1 Protein; Gamma-Synuclein; Synoretin; PERSYN; PRSN; Synoretin

Function:

This gene encodes a member of the synuclein family of proteins which are believed to be involved in the pathogenesis of neurodegenerative diseases. Mutations in this gene have also been associated with breast tumor development.

Plays a role in neurofilament network integrity. May be involved in modulating axonal architecture during
development and in the adult. In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in skin. Activates the MAPK and Elk-1 signal transduction pathway

Chromosomal Localization:

10q23.2-q23.3

Expression System:

NCBI Accession Number:

NP_003078.2

Swiss Prot Accession Number:

O76070

DNA Source:

N/A

Immunogen:

Synthetic Peptide

Vector Name:

N/A

Extinction Coefficient:

Buffers:

Expressed Sequence:

TVEEAENIAVTSGVVR

Native Sequence:

Calculated Isoelectric Point:

0

Molecular Weight:

1760

Last Updated:

06/21/2013

Links

Characterization Data

SOPs

No SOPs available.

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