TERRY CONNELL, PhD personal profile
A major focus of my laboratory is to investigate the cellular and molecular events which modulate mucosal immune responses. We have demonstrated that LT-IIa and LT-IIb, two Type II heat-labile enterotoxins of Escherichia coli, are potent oral and nasal immunogens that have the capacity for augmenting humoral and cellular immune responses . Using a variety of immunological and cellular techniques (including flow cytometry, FRET fluorescent detection, cytokine multiplex analysis, mutagenesis, and the use of transgenic mice), we are evaluating the manners in which these two immunomodulators productively interact with various lymphoid cells such as T cells, B cells, and dendritic cells to induce or suppress cytokine production, co-stimulatory ligand expression, and proliferation.
Department of Oral Biology
629 BRB
Buffalo, NY 14214
Phone: (716) 829-2844
Fax: (716) 829-3942
Department Chair
Stefan Ruhl, DDS, PhD
shruhl@buffalo.edu
Assistant to the Chair
Kurt Winter, PhD
kwinter@buffalo.edu