ted resistance to vaginal reinfection." name=ted resistance to vaginal reinfection." ted resistance to vaginal reinfection." ted resistance to vaginal reinfection." nameted resistance to vaginal reinfection." /> /> /> /> /> /> /> /> /> /> /> /> /> /> /> "> "> "> OAS_A"> "> OAS_AD('Top'); "> "> OAS_AD('Top');"> OAS_AD('Top'); "> OAS_AD('Top'); "> OAS_AD('Top'); fic, antibody-mediated resistance to vaginal reinfection.fic, antibody-mediatefic, antibody-mediated resistance to vaginal fic, antibody-mediated resistance to vaginal reinfection. fic, antibody-mediated resistance to vaginal reinfection.
    fic, antific,fic, antibody-mediated resistanfic, antibody-mediated resific, antibody-mediated resistance to vaginal reinfection.
      fic, antibofic,fic, antibody-mediated resistanfic, antibody-mediated resific, antibody-mediated resistance to vaginal reinfection.
        fic, antific,fic, antibody-mediated resistanfic, antibody-mediated resific, antibody-mediated resistance to vaginal reinfection.

        ABSTRACT

        Oophorectomized, estrogen-treated rats were susceptible to experimental vaginal infection by Candida albicans. After spontaneous clearing of the primary infection, the animals were highly resistant to a second vaginal challenge with the fungus. The vaginal fluid of Candida-resistant rats contained antibodies directed against mannan constituents and secretory aspartyl proteinase(s) of C. albicans and was capable of transferring a degree of anti-Candida protection to naive, nonimmunized rats. This passive protection was mediated by the immunoglobulin fraction of the vaginal fluid and was substantially abolished by preabsorption of the vaginal fluid with C. albicans, but not with Saccharomyces cerevisiae, cells. Vaginal anti-mannan antibodies were also produced by active immunization with heat-killed cells of C. albicans or with a mannan extract when administered via the vaginal route. The protection conferred was comparable to that resulting frocteriology and Medical Mycology, Istitucteriocteriology and Medical Mycology, Istituto Superiorcteriolcteriology and Medicteriology and Medical Mycology, Istituto Superiore di Sanità, Rcteriology and Medical Mycology, Istituto Superiore dcteriology and Medical Mycology, Istituto Superiore di Sanititeulike">Add to CiteULikeiteuiteulike">Add to Reddit-boo-bookmarking-item-reddit">

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