<<<<< blisher" content="Cold Spring Harbor Laboratory" /> African/Eurasian pastoralist groups arriving >1,000 years African/Eurasian pastoralist groups arriving >1,000 ye African/Eurasian pastoralist groups arriving >1,000 y African/Eurasian pastoralist groups arriving >1, African/Eurasian pastoralist groups arriving >1,000 year African/Eurasian pastoralist groups arriving >1,00 African/Eurasian pastoralist groups arriving >1,000 yea African/Eurasian pastoralist groups arriving >1,00 African/Eurasian pastoralist groups arriving >1,000 African/Eurasian pastoralist groups arriving >1,000 y African/Eurasian pastoralist groups arrtias Jakobsson" /> tias Jakobsson" /> by 9-22% genetic admixture from East African/Eurasian pastoraby 9-22% genetic admixture from East African/Eurasian pastorby 9-22% genetic admixture from East African/Eurasian by 9-22% genetic admixture from East African/Eurasian pastoralist groups arriving >1,000 years ago, including the Ju|'hoansi San, pby 9-22% genetic admixture from East African/Eurasian pastoralist groups arriving >1,000 years ago, including the Ju|'hoansi San, previously thought to have very low levels of admixture. Using traditional and new approaches, we estimate the population divergence t and West Africa or Eurasia in the last 1,700 years, we generated and analyzed genome sequence data from seven ancient individuals from KwaZulu-Natal, South Africa. Three Stone Age hunter-gatherers date to ~2,000 years ago, and we show that they were related to current-day southern San groups such as the Karretjie People. Four Iron Age farmers (300-500 years old) have genetic signatures similar to present day Bantu-speakers. The genome sequence (13x coverage) of a juvenile boy from Ballito Bay, who lived ~2,000 years ago, demonstrates that southern African Stone Age hunter-gatherers were not impacted by recent admixture; however, we estimate that all modern-day Khoekhoe and San groups have been influenced by 9-22% genetic admixture from East African/Eurasian pastoralist groups arriving &gt;1,000 years ago, including the Ju|9hoansi San, previously thought to have very low levels of admixture. Using traditional and new approaches, we estimate the population divergence time between the Ballito Bay boy and other groups to beyond 260,000 years ago. These estimates dramatically increases the deepest divergence amongst modern humans, coincide with the onset of the Middle Stone Age in sub-Saharan Africa, and coincide with anatomical developments of archaic humans into modern humans as represented in the local fossil record. Cumulatively, cross-disciplinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot spot9 for the evolution of our species.</p>" /> linary records increasingly point to southern Africa as alinary records increasingly point to southern Africa as a potential (not nelinary records increasingly point to southern Africa as a potenlinary records increasingly point to southern Africa as alinary records increasingly point to southern Alinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot slinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot spot9 for the evolinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot spot9 forlinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot spot9 flinary records increasingly point to southern Africa alinary records increasingly point to southern Africa alinary records increasingly point to southern Africa aslinary records increasingly point to southern Africalinary records increasingly point to southern Africa as a potelinary records increasingly point to southern Africa as a potential (not nlinary records increasingly point to southern Africa as a potential (not neclinary records increasingly point to southern Afri/orcid.org/0000-0002-8160-9621" /> /orcid.org/0000-0002-8160-9621" /> s" /> ontent="width=device-width, initial-scale=1, maximum-scale=3, minimum-scale=1, user-scalable=yes" /> oontenontent="width=device-width, initial-scale=1, maximum-scale=3, minimum-scale=1, user-scalable=yes" /> oooqqqtip.min.css" media="all" /> qtqtip.min.css" media="all" /> eefefault/files/advagg_css/css__ElJr3PIJEvw3qLXc1cnYiLj2G4KgDPSXFOfm6Phf8hw__JdWGm15cDWjsK6KrFlQVXQix9YgNeYysf22XZHj-Y-c__9r7Th_-OuSCm3V-vY_RxCnFCjJ5YEegohFPCNOnX7_w.css" media="all" /> =="https:/="https://ww="https://www.biorxiv.org/sites/default/files/advagg_css/css__cbEguwW7XBe1A1mKHxDa1D-hVUxyfsrmrTERI5gTvMc__cMSF5qncLLfwepMmTv8loLSZaXQMLjq4mQv-SaXAtoE__9r7Th_-OuSCm3V-vY_RxCnFCjJ5YEegohFPCNOnX7_w.css" media="all" /> ,, < l":"al":"all and (min-width: 980px) and (min-device-width: 980px), all and (max-device-width: 1024px) and (min-l":"all anl":"all and (min-width: 980px) and (min-device-width: 980px), all and (max-device-width: 1024px) and (min-width: 1024px) and (orientation:landscape)","wide":"all and (min-width: 1220px)"}}}}); //-->l":"all and (min-width: 980pl":"all an