tp://www.w3.org/1999/xhtml" xmlns:mml="http://www.w3.org/1998/Math/MathML"> old Spring Harbor Laboratory. This pre-print is availold Spring Harbor Laboratory. This pre-print is available under a Creative Commons License (Attribution-NonCommercial-NoDerivs 4.0 International), CC BY-NC-ND 4.0, as described at http://creativecommons.org/licenses/by-nc-nd/4.0/" /> sly thought to have very low levels of admixture. Using tradisly thought to have very low levels of admixture. Using trsly thought to have very low levels of admixture. Using tsly thought to have very low levels of admixture. Ussly thought to have very low levels of admixture. Using tradsly thought to have very low levels of admixture. Usinsly thought to have very low levels of admixture. Using trasly thought to have very low levels of admixture. Usinsly thought to have very low levels of admixture. Using sly thought to have very low levels of admixture. Using tsly thought to have very low levels of admixture. Using trasly thought to have very low levels of admixture. Using traditional and new approachean divergence beyond 260,000 years ago" /> an divergence beyond 260,000 years ago" /> lation divergence time between the Ballitolation divergence time between the Ballito Bay boy and otherlation divergence time between the Ballito Bay boy andlation divergence time between the Ballito Bay boy and other groups to beyond 260,000 years ago. These estimates dramatically increaselation divergence time between the Ballito Bay boy and other groups to beyond 260,000 years ago. These estimates dramatically increases the deepest divergence amongst modern humans, coincide with the onset of the Middle Stone Age in sub-Saharan Africa, and coincide with anatomical developments of archaic humans into modern humans as represented in the local fossil record. Cumulatively, cross-disciplinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 'hot spot' for the evolution of our ent-day southern San groups such as the Karretjie People. Four Iron Age farmers (300-500 years old) have genetic signatures similar to present day Bantu-speakers. The genome sequence (13x coverage) of a juvenile boy from Ballito Bay, who lived ~2,000 years ago, demonstrates that southern African Stone Age hunter-gatherers were not impacted by recent admixture; however, we estimate that all modern-day Khoekhoe and San groups have been influenced by 9-22% genetic admixture from East African/Eurasian pastoralist groups arriving &gt;1,000 years ago, including the Ju|9hoansi San, previously thought to have very low levels of admixture. Using traditional and new approaches, we estimate the population divergence time between the Ballito Bay boy and other groups to beyond 260,000 years ago. These estimates dramatically increases the deepest divergence amongst modern humans, coincide with the onset of the Middle Stone Age in sub-Saharan Africa, and coincide with anatomical developments of archaic humans into modern humans as represented in the local fossil record. Cumulatively, cross-disciplinary records increasingly point to southern Africa as a potential (not necessarily exclusive) 9hot spot9 for the evolution of our species.</p>" /> ent-day southern San groups such as the Karretjie People.ent-day southern San groups such as the Karretjie Peoplrbor Laboratory" /> rbor Laboratory" /> ation_author_orcid" content="http://orcid.org/0000-0002-64ation_author_orcid" content="http://orcid.org/0000-0002-6456-8055" /> ation_author_orcid" content="http://orcid.org/0000-0002-6456-ation_author_orcid" content="http://orcid.org/0000-0002-6456-8055" /> University of the Witwatersrand;" /> " /> "" /> " /> """"nvnvg6AoHY.css" media="all" /> tt/// /I and and (min-width: 1220px)"}}}}); //--> and (min and (min-wi and (min-width: 122 and (min and (min-width and (min-width: 1220px)"}}}}); //--> e-branding clearfix print-display-block container-30"> bmbmit" idbmit" id=bmit" id="edibmit" ibmit" id=bmit" ibmit" id="ebmit" id=bmit" ibmit" idbmit" ibmit" id v>
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