University at Buffalo - The State University of New York
Skip to Content
PubMed Central, Figure 3: J Signal Transduct. 2012; 2012: 308943. Published online 2012 Jan 23. doi:  10.1155/2012/308943
Logo of jstJournal of Signal Transduction
PMC full text:

Figure 3

An external file that holds a picture, illustration, etc.
Object name is JST2012-308943.003.jpg

A. actinomycetemcomitans LPS induces significant linear bone loss which is blocked by SD-282. (a) Reformatted μCT isoform display from 8 weeks A. actinomycetemcomitans LPS-injected rat maxillae exhibits dramatic palatal and interproximal bone loss. Landmarks used for linear measurements were the cementoenamel junction (CEJ) to the alveolar bone crest (ABC). Differences between these anatomical locations using defined locations of 2D displays determined alveolar bone loss. (b) Linear bone loss as measured from the CEF to AB (Mean ± SEM). Significant bone loss (P < 0.01) was observed between control (n = 6) and A. actinomycetemcomitans LPS injected rats (n = 12). Significant reduction of LPS-induced periodontal bone loss (**P < 0.01 for SD-282 [15 mg/kg; n = 8] and *P < 0.05 for SD-282 [45 mg/kg; n = 8]) [105]. Reproduced with permission.

Images in this article

  • Figure 1
  • Figure 2
  • Figure 3
  • Figure 4
  • Figure 5
  • Figure 6
Click on the image to see a larger version.