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Genetics. 2013 Aug;194(4):1037-9. doi: 10.1534/genetics.113.152181. Epub 2013 May 24.

SLiM: simulating evolution with selection and linkage.

Author information

1
Department of Biology, Stanford University, Stanford, CA 94305, USA. messer@stanford.edu

Abstract

SLiM is an efficient forward population genetic simulation designed for studying the effects of linkage and selection on a chromosome-wide scale. The program can incorporate complex scenarios of demography and population substructure, various models for selection and dominance of new mutations, arbitrary gene structure, and user-defined recombination maps.

KEYWORDS:

background selection; genetic hitchhiking; population genetic simulation

PMID:
23709637
PMCID:
PMC3730910
DOI:
10.1534/genetics.113.152181
[Indexed for MEDLINE]
Free PMC Article
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