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Acta Odontol Scand. 1989 Apr;47(2):111-6.

Thin-section transmission electron microscopy of human saliva.

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Department of Prosthetic Dentistry, Faculty of Dentistry, University of Lund, Malmö, Sweden.


Thin sections (90-100 nm) of flash-frozen human saliva fractions and whole saliva were examined by transmission electron microscopy. Inside the major filamentous structural components numerous ultrastructural details were observed, especially for whole saliva and submandibular/sublingual fractions. An outer reticulated zone believed to contain the major salivary glycoproteins surrounded an inner core consisting of a continuous, more electron dense phase with multiple vacuoles and granules of different sizes, shapes, and electron densities. The observed structures suggest a complex microarchitectural model for whole saliva.

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