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ΔNp63 is expressed during early mouse embryonic skin development.
Isoform specific expression of p63 was analyzed during various stages of skin development using three antibodies recognizing different p63 variants. Far left panel (panel 1) are H&E staining of skin using paraffin embedded whole embryos. Panel 2 demonstrates expression of ΔNp63 (green) using the RR-14 antibody. Panel 3 shows expression of p63α (green) using the H-129 antibody. K5 and K14 expression is also shown in green (panels 3 and 4 respectively). Far right panel reveals that TAp63 expression is absent during the developmental windows examined. Scale bar: 50 µm.