Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
ΔNp63 and TAp63 TF networks. (a) Interaction Network for ΔNp63. Green molecules denote predicted co-regulators. Red arrows represent TFs that are likely direct targets of p63 as determined by overlay with ChIP-Seq information. Molecules with blue boundaries are those involved in Hair and Skin development and function. (b) Interaction Network of TAp63. Molecules denoted in blue are the predicted co-regulators. Molecules with green boundaries are involved in lymphoid tissue structure and development. The interaction networks (black lines connecting molecules) were generated by QIAGEN’s Ingenuity Pathway Analysis. The specific type of evidence in literature is denoted by–PP: Protein-Protein interaction, A: Activation, I: Inhibition, T: Transcription, E: Expression, PD: Protein-DNA interaction