Salivary proteomics in biomedical research

A Zhang, H Sun, P Wang, X Wang - Clinica Chimica Acta, 2013 - Elsevier
Proteins that are important indicators of physiological or pathological states, can provide
information for the identification of early and differential markers for disease. Saliva, contains
an abundance of proteins, offers an easy, inexpensive, safe, and non-invasive approach for

Periodontal disease immunology:'double indemnity'in protecting the host

JL Ebersole, DR Dawson, LA Morford… - Periodontology …, 2013 - Wiley Online Library
Abstract During the last two to three decades our understanding of the immunobiology of
periodontal disease has increased exponentially, both with respect to the microbial agents
triggering the disease process and the molecular mechanisms of the host engagement

Quantitative analysis of the intra‐and inter‐subject variability of the whole salivary proteome

N Jehmlich, KHD Dinh… - Journal of …, 2013 - Wiley Online Library
Results In the 2-D DIGE experiment, the median coefficient of variation (CV) for intra-subject
variability was significantly lower (CV of 0.39) than that for inter-subject variability (CV of
0.57; CV of technical replicates 0.17). LC-MS/MS data confirmed the significantly lower

[PDF][PDF] Saliva as an ideal milieu for emerging diagnostic approaches in primary Sjögren's syndrome

C Baldini, A Gallo, P Perez, M Mosca… - Clinical and …, 2012 -
1Rheumatology Unit, University of Pisa, Pisa, Italy; 2Sjögren's Syndrome Clinic, Molecular Physiology
and Therapeutics Branch, National Institute of Dental and Cranio- facial Research, National Institutes
of Health, Bethesda, Maryland, USA. Chiara Baldini, MD Alessia Gallo, PhD Paola Perez, PhD

Proteomics and proteogenomics approaches for oral diseases

NL Bragazzi, E Pechkova… - Adv Protein Chem Struct …, 2014 -
Abstract Design and implementation of new biocompatible materials and achievements in
the field of nanogenomics and nanoproteomics as well as in other related and allied
sciences in the broader framework of translational and clinical nanomedicine are paving

Host defense proteins derived from human saliva bind to Staphylococcus aureus

SM Heo, KS Choi, LA Kazim, MS Reddy… - Infection and …, 2013 - Am Soc Microbiol
ABSTRACT Proteins in human saliva are thought to modulate bacterial colonization of the
oral cavity. Yet, information is sparse on how salivary proteins interact with systemic
pathogens that transiently or permanently colonize the oral environment. Staphylococcus

Implications of salivary protein binding to commensal and pathogenic bacteria

SM Heo, S Ruhl, FA Scannapieco - Journal of oral biosciences, 2013 - Elsevier
Abstract An important function of salivary proteins is to interact with microorganisms that
enter the oral cavity. For some microbes, these interactions promote microbial colonization.
For others, these interactions are deleterious and result in the elimination of the microbe

[HTML][HTML] Great Expectorations: The Potential of Salivary “Omic” Approaches in Neonatal Intensive Care

JA Romano-Keeler, JL Wynn… - Journal of perinatology …, 2014 -
Abstract Among those that require critical care, preterm neonates have the greatest
limitations on available blood or body fluids for clinical or research-based assessments.
Recent technological advancements have improved our ability to detect genetic, proteomic

Continuous, quantitative monitoring of roxithromycin in human saliva by flow injection chemiluminescence analysis

X Tan, Z Song - Applied spectroscopy, 2013 -
Human saliva quantitative monitoring of roxithromycin (ROX) at picomolar-level by flow
injection (FI) chemiluminescence (CL) analysis is described for the first time, to our
knowledge. Monitoring was based on the CL intensity from luminol–BSA reaction, which can

[HTML][HTML] Towards further defining the proteome of mouse saliva

AA Blanchard, P Ezzati… - Proteome …, 2015 -
Background Knowledge of the mouse salivary proteome is not well documented and as a
result, very limited. Currently, several salivary proteins remain unidentified and for some
others, their function yet to be determined. The goal of the present study is to utilize mass