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Quintessence Int. 2015 Mar;46(3):247-53. doi: 10.3290/j.qi.a32921.

Indications and procedures for direct immunofluorescence biopsies of the oral mucosa.

Abstract

A definitive diagnosis is crucial for management of any oral mucosal disease. Direct immunofluorescence (DIF) is a valuable diagnostic aid for immune-mediated blistering diseases and systemic connective tissue diseases of the skin and the mucosa. This paper gives an overview of the DIF biopsy technique for oral lesions and provides a background for the clinician to optimize the utilization of DIF biopsy. The key characteristic diagnostic findings of DIF of specific mucosal diseases are also discussed.

PMID:
25328923
DOI:
10.3290/j.qi.a32921
[Indexed for MEDLINE]
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