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PubMed Central, Figure 2: Nature. 2015 Oct 1; 526(7571): 75–81. doi:  10.1038/nature15394
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Nature. Author manuscript; available in PMC 2016 Apr 1.
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Nature. 2015 Oct 1; 526(7571): 75–81.
doi:  10.1038/nature15394

Figure 2

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SV functional impact

a. Relative enrichment or depletion of genomic elements within breakpoint-resolved deletions binned by VAF. TF, transcription factor binding site; nc, noncoding. RVIS range from 0–100 (low <20, medium 20–50, high ≥50). *no element intersected. b. Enrichment/depletion of genomic elements within different SV classes, compared with breakpoint-resolved deletions. c. Manhattan plot of DUSP22-eQTL. Inset: boxplots of association between copy-number genotype and expression. d. Manhattan plot of ZNF43-eQTL. e. Enrichment of SV-containing haplotypes at previously reported GWAS hits (error bars show s.e.m.).

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