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Items: 1 to 20 of 91

1.

ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis.

Rizzo JM, Oyelakin A, Min S, Smalley K, Bard J, Luo W, Nyquist J, Guttman-Yassky E, Yoshida T, De Benedetto A, Beck LA, Sinha S, Romano RA.

Cell Death Differ. 2016 Jun;23(6):1073-85. doi: 10.1038/cdd.2015.162. Epub 2016 Jan 15.

2.

Epidermal overexpression of transgenic ΔNp63 promotes type 2 immune and myeloid inflammatory responses and hyperplasia via NF-κB activation.

Du J, Romano RA, Si H, Mattox A, Bian Y, Yang X, Sinha S, Van Waes C, Chen Z.

J Pathol. 2014 Feb;232(3):356-68. doi: 10.1002/path.4302.

PMID:
24258200
3.

A chromatin immunoprecipitation screen in mouse keratinocytes reveals Runx1 as a direct transcriptional target of DeltaNp63.

Ortt K, Raveh E, Gat U, Sinha S.

J Cell Biochem. 2008 Jul 1;104(4):1204-19. doi: 10.1002/jcb.21700.

PMID:
18275068
4.

Keratinocytes in atopic dermatitis express abundant ΔNp73 regulating thymic stromal lymphopoietin production via NF-κB.

Kumagai A, Kubo T, Kawata K, Kamekura R, Yamashita K, Jitsukawa S, Nagaya T, Sumikawa Y, Himi T, Yamashita T, Ichimiya S.

J Dermatol Sci. 2017 Jun 22. pii: S0923-1811(17)30779-X. doi: 10.1016/j.jdermsci.2017.06.017. [Epub ahead of print]

PMID:
28655470
5.

ΔNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation.

Romano RA, Smalley K, Magraw C, Serna VA, Kurita T, Raghavan S, Sinha S.

Development. 2012 Feb;139(4):772-82. doi: 10.1242/dev.071191.

6.

Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice.

Wang Z, Zhang LJ, Guha G, Li S, Kyrylkova K, Kioussi C, Leid M, Ganguli-Indra G, Indra AK.

PLoS One. 2012;7(12):e51262. doi: 10.1371/journal.pone.0051262. Epub 2012 Dec 20.

7.

An active role of the DeltaN isoform of p63 in regulating basal keratin genes K5 and K14 and directing epidermal cell fate.

Romano RA, Ortt K, Birkaya B, Smalley K, Sinha S.

PLoS One. 2009 May 20;4(5):e5623. doi: 10.1371/journal.pone.0005623.

8.

ΔNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.

Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S.

PLoS One. 2014 Aug 29;9(8):e105498. doi: 10.1371/journal.pone.0105498. eCollection 2014.

9.

Intrinsic atopic dermatitis shows similar TH2 and higher TH17 immune activation compared with extrinsic atopic dermatitis.

Suárez-Fariñas M, Dhingra N, Gittler J, Shemer A, Cardinale I, de Guzman Strong C, Krueger JG, Guttman-Yassky E.

J Allergy Clin Immunol. 2013 Aug;132(2):361-70. doi: 10.1016/j.jaci.2013.04.046. Epub 2013 Jun 15.

10.

Tight junction protein claudin-4 is modulated via ΔNp63 in human keratinocytes.

Kubo T, Sugimoto K, Kojima T, Sawada N, Sato N, Ichimiya S.

Biochem Biophys Res Commun. 2014 Dec 12;455(3-4):205-11. doi: 10.1016/j.bbrc.2014.10.148. Epub 2014 Nov 4.

PMID:
25449274
11.
12.

Differential expression of inflammation-related genes in IL-4 transgenic mice before and after the onset of atopic dermatitis skin lesions.

Bao L, Zhang H, Mohan GC, Shen K, Chan LS.

Mol Cell Probes. 2016 Feb;30(1):30-8. doi: 10.1016/j.mcp.2015.11.001. Epub 2015 Nov 14.

PMID:
26585782
13.

Activation of human eosinophils and epidermal keratinocytes by Th2 cytokine IL-31: implication for the immunopathogenesis of atopic dermatitis.

Cheung PF, Wong CK, Ho AW, Hu S, Chen DP, Lam CW.

Int Immunol. 2010 Jun;22(6):453-67. doi: 10.1093/intimm/dxq027. Epub 2010 Apr 21.

PMID:
20410259
14.

Type 2 helper T-cell cytokines induce morphologic and molecular characteristics of atopic dermatitis in human skin equivalent.

Kamsteeg M, Bergers M, de Boer R, Zeeuwen PL, Hato SV, Schalkwijk J, Tjabringa GS.

Am J Pathol. 2011 May;178(5):2091-9. doi: 10.1016/j.ajpath.2011.01.037.

15.

The Expression and Regulation of Interleukin-33 in Human Epidermal Keratinocytes: A New Mediator of Atopic Dermatitis and Its Possible Signaling Pathway.

Du HY, Fu HY, Li DN, Qiao Y, Wang QW, Liu W.

J Interferon Cytokine Res. 2016 Sep;36(9):552-62. doi: 10.1089/jir.2015.0159. Epub 2016 Jun 27.

PMID:
27348082
17.

A Role of Staphyococcus aureus, Interleukin-18, Nerve Growth Factor and Semaphorin 3A, an Axon Guidance Molecule, in Pathogenesis and Treatment of Atopic Dermatitis.

Ikezawa Z, Komori J, Ikezawa Y, Inoue Y, Kirino M, Katsuyama M, Aihara M.

Allergy Asthma Immunol Res. 2010 Oct;2(4):235-46. doi: 10.4168/aair.2010.2.4.235. Epub 2010 May 12.

18.

Dynamic life of a skin keratinocyte: an intimate tryst with the master regulator p63.

Romano RA, Sinha S.

Indian J Exp Biol. 2011 Oct;49(10):721-31. Review.

PMID:
22013738
19.

Keratinocytes from patients with atopic dermatitis and psoriasis show a distinct chemokine production profile in response to T cell-derived cytokines.

Giustizieri ML, Mascia F, Frezzolini A, De Pità O, Chinni LM, Giannetti A, Girolomoni G, Pastore S.

J Allergy Clin Immunol. 2001 May;107(5):871-7.

PMID:
11344355
20.

Ras and TGF-β signaling enhance cancer progression by promoting the ΔNp63 transcriptional program.

Vasilaki E, Morikawa M, Koinuma D, Mizutani A, Hirano Y, Ehata S, Sundqvist A, Kawasaki N, Cedervall J, Olsson AK, Aburatani H, Moustakas A, Miyazono K, Heldin CH.

Sci Signal. 2016 Aug 23;9(442):ra84. doi: 10.1126/scisignal.aag3232.

PMID:
27555661

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