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Nat Chem Biol. 2009 Sep;5(9):612-3. doi: 10.1038/nchembio0909-612.

A Golgi-on-a-chip for glycan synthesis.

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1
Department of Cellular and Molecular Medicine, Glycobiology Research and Training Center, University of California-San Diego, La Jolla, California, USA.

Abstract

One of the primary functions of the Golgi apparatus is the assembly of glycans on macromolecules destined for secretion or the plasma membrane. A recent study describes the first step toward an artificial Golgi, based on a microfluidic chip and magnetic nanoparticles.

PMID:
19690535
DOI:
10.1038/nchembio0909-612
[Indexed for MEDLINE]
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