Geographic distribution and adaptive significance of genomic structural variants: an anthropological genetics perspective

M Eaaswarkhanth, P Pavlidis, O Gokcumen - Human biology, 2014 - BioOne
ABSTRACT Anthropological geneticists have successfully used single-nucleotide and short
tandem repeat variations across human genomes to reconstruct human history. These
markers have also been used extensively to identify adaptive and phenotypic variation. The
recent advent of high-throughput genomic technologies revealed an overlooked type of
genomic variation: structural variants (SVs). In fact, some SVs may contribute to human ...