A plaque assay for all cells secreting Ig of a given type or class

E Gronowicz, A Coutinho… - European journal of …, 1976 - Wiley Online Library
Abstract A modification of the hemolytic plaque assay using protein A-coated red cells is
described which makes use of the fact that the Fc portion of IgG binds to protein A. A number
of murine plasmacytomas secreting different classes of Ig have been tested for plaque

Prognostic value of HIV-1 syncytium-inducing phenotype for rate of CD4+ cell depletion and progression to AIDS

…, MTL Roos, RA Coutinho… - Annals of internal …, 1993 - Am Coll Physicians
Objective: To investigate the relation between detection of syncytium-inducing (SI), human
immunodeficiency virus type 1 (HIV-1) variants, rate of CD4+ cell decline, and clinical
progression. Design: Prospective study during a 2.5-year follow-up period; cohort study with

[HTML][HTML] Electron reconstruction and identification efficiency measurements with the ATLAS detector using the 2011 LHC proton–proton collision data

…, MG Alviggi, K Amako, YA Coutinho… - The European Physical …, 2014 - Springer
Abstract Many of the interesting physics processes to be measured at the LHC have a
signature involving one or more isolated electrons. The electron reconstruction and
identification efficiencies of the ATLAS detector at the LHC have been evaluated using

Persistent immune activation in HIV-1 infection is associated with progression to AIDS

…, SA Otto, BHB van Benthem, MTL Roos, RA Coutinho… - Aids, 2003 - journals.lww.com
Background: HIV-1 infection is characterized by chronic generalized CD8 and CD4 T cell
hyperactivation, the biological effect of which is not understood. Objective: To study the
relation between chronic immune activation and CD4 T cell depletion in HIV-1 infection.

Expression of human immunodeficiency virus antigen (HIV-Ag) in serum and cerebrospinal fluid during acute and chronic infection

…, WJA Krone, EC Wolters, JM Oleske, RA Coutinho - The lancet, 1986 - Elsevier
Abstract Human immunodeficiency virus antigen (HIV-Ag) was detected in the serum of most
adult (13/16) and paediatric (6/6) AIDS patients and rarely in the serum of symptomless
seropositive controls (1/13). It was present in the cerebrospinal fluid (CSF) of all 5 children

Jet energy measurement and its systematic uncertainty in proton–proton collisions at\sqrt {s}= 7 TeV with the ATLAS detector

…, MG Alviggi, K Amako, YA Coutinho… - The European Physical …, 2015 - Springer
Abstract The jet energy scale (JES) and its systematic uncertainty are determined for jets
measured with the ATLAS detector using proton–proton collision data with a centre-of-mass
energy of\(\sqrt {s}= 7\) TeV corresponding to an integrated luminosity of\(4.7\)\(\,\,\text {fb}^{-

[HTML][HTML] Measurement of the muon reconstruction performance of the ATLAS detector using 2011 and 2012 LHC proton–proton collision data

…, MG Alviggi, K Amako, YA Coutinho… - The European Physical …, 2014 - Springer
Abstract This paper presents the performance of the ATLAS muon reconstruction during the
LHC run with pp pp collisions at s= 7 s= 7–8 TeV in 2011–2012, focusing mainly on data
collected in 2012. Measurements of the reconstruction efficiency and of the momentum scale

Combined Measurement of the Higgs Boson Mass in pp Collisions at s= 7 and 8 TeV with the ATLAS and CMS Experiments

…, MG Alviggi, BT Amadio, K Amako, YA Coutinho… - Physical review …, 2015 - APS
Abstract A measurement of the Higgs boson mass is presented based on the combined data
samples of the ATLAS and CMS experiments at the CERN LHC in the H→ γ γ and H→ ZZ→
4 ℓ decay channels. The results are obtained from a simultaneous fit to the reconstructed

Natural autoantibodies

A Coutinho, MD Kazatchkine, S Avrameas - Current opinion in immunology, 1995 - Elsevier
Autoantibodies of the IgM, IgG and IgA classes, reactive with a variety of serum proteins, cell
surface structures and intracellular structures, are 'naturally'found in all normal individuals.
Present in human cord blood and in 'antigen-free'mice, their variable-region repertoire is

Macrophage-tropic variants initiate human immunodeficiency virus type 1 infection after sexual, parenteral, and vertical transmission.

…, J Veenstra, K Boer, RA Coutinho… - Journal of Clinical …, 1994 - ncbi.nlm.nih.gov
Abstract Macrophage-tropic, non-syncytium-inducing, HIV-1 variants predominate in the
asymptomatic phase of infection and may be responsible for establishing infection in an
individual exposed to the mixture of HIV-1 variants. Here, genotypical and phenotypical