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Arthritis
 

Arthritis

Common Name(s)

Arthritis

Arthritis is the inflammation of a joint (the point where two bones fit together). There are many types of arthritis and each one has its own cause and symptoms. Typically, all forms of arthritis are associated with symptoms that include pain, stiffness, swelling, redness, and decreased range of motion in the joint that usually gets worse with age. Severe arthritis that affects the hands and arms may make it difficult to do daily tasks while arthritis that affects the knees or ankles may make it difficult to walk or stand. The most common types of arthritis are osteoarthritis and rheumatoid arthritis (RA). Osteoarthritis is caused by the breakdown of the hard tissue that covers and protects the ends of bones (cartilage). Rheumatoid arthritis (RA) is an autoimmune disease that causes the body’s immune system to attack the lining of joints (synovium).

Risk factors for arthritis include a family history of arthritis, increasing age, previous joint injury, obesity and gender, as women are more likely than men to develop RA. Causes of other forms of arthritis include a build up of uric acid crystals in the joint, infections, or underlying disease, such as psoriasis or lupus. Your doctor may use a physical exam, imaging, lab tests and video assessment of your joints to diagnosis arthritis. Imaging can include an X-ray and an MRI to get a detailed look at the joint and cartilage. Doctors may also perform arthroscopy, which uses a small video camera inserted into a small cut near the affected joint to obtain images of the affected area. Although there is no cure for arthritis, there are treatments that help reduce symptoms. These include pain medications, therapy and surgery. If you or someone in your family has been diagnosed with arthritis, talk with a doctor to determine the best treatment plan.

Source: Advocacy organizations associated with the condition.

 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

Last Updated: 24 Sep 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Arthritis" for support, advocacy or research.

International Scleroderma Network

Our mission is to provide stellar worldwide research, support, education and awareness for scleroderma and related illnesses.

http://www.sclero.org/

Last Updated: 18 Apr 2010

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US Pain Foundation

US Pain Foundation is created by people with pain for people with pain. As a 501 (c)3 non-profit organization dedicated to serving those who live with pain conditions and their care providers, U.S. Pain Foundation exists to help individuals find resources and inspiration.
Our mission is simple: to educate, connect, inform, advocate and empower those living with pain. In addition we work to educate the public on pain issues and to raise awareness on pain in America. We recognize and validate the 100 million Americans who battle pain every day by offering positive programs that empower and ed

http://www.uspainfoundation.org

Last Updated: 24 Sep 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Arthritis" returned 14601 free, full-text research articles on human participants. First 3 results:

Norwegian scabies in a patient treated with Tripterygium glycoside for rheumatoid arthritis.
 

Author(s): Xiaolin Bu, Juan Fan, Xiaoli Hu, Xinling Bi, Bin Peng, Denghai Zhang

Journal: An Bras Dermatol. ;92(4):556-558.

 

We report an 80-year-old male patient with severe rheumatoid arthritis who was treated with tripterygium glycoside, an immunosuppressive agent made from the extract of a Chinese medicinal herb called Tripterygium wilfordii Hook F. The patient had no apparent skin lesions before the ...

Last Updated: 27 Sep 2017

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DMARD use is associated with a higher risk of dementia in patients with rheumatoid arthritis: A propensity score-matched case-control study.
 

Author(s): Ming-Hsien Chou, Jong-Yi Wang, Cheng-Li Lin, Wei-Sheng Chung

Journal: Toxicol. Appl. Pharmacol.. 2017 Nov;334():217-222.

 

Patients with rheumatoid arthritis (RA) exhibit an increased risk of dementia. Disease-modifying antirheumatic drugs (DMARDs) are commonly used to slow RA progression, but studies investigating the relationship between DMARDs and dementia in patients with RA are lacking. We investigated ...

Last Updated: 20 Sep 2017

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B-cell phenotype and IgD-CD27- memory B cells are affected by TNF-inhibitors and tocilizumab treatment in rheumatoid arthritis.
 

Author(s): Rita A Moura, Cláudia Quaresma, Ana R Vieira, Maria J Gonçalves, Joaquim Polido-Pereira, Vasco C Romão, Nádia Martins, Helena Canhão, João E Fonseca

Journal:

 

The use of TNF-inhibitors and/or the IL-6 receptor antagonist, tocilizumab, in rheumatoid arthritis (RA) have pleiotropic effects that also involve circulating B-cells. The main goal of this study was to assess the effect of TNF-inhibitors and tocilizumab on B-cell phenotype and gene ...

Last Updated: 8 Sep 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Arthritis" returned 1758 free, full-text review articles on human participants. First 3 results:

HLA class II and rheumatoid arthritis: the bumpy road of revelation.
 

Author(s): Arieke S B Kampstra, René E M Toes

Journal: Immunogenetics. 2017 Aug;69(8-9):597-603.

 

Rheumatoid arthritis (RA) is a chronic auto-immune disease primarily targeting the joints. Approximately 1% of the population is affected by RA, and despite the improvements in therapeutic interventions, elucidation of the disease pathogenesis is still in its infancy. RA patients ...

Last Updated: 11 Jul 2017

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Prediction of Response to Targeted Treatment in Rheumatoid Arthritis.
 

Author(s): C A Wijbrandts, P P Tak

Journal: Mayo Clin. Proc.. 2017 Jul;92(7):1129-1143.

 

Rheumatoid arthritis is an autoimmune syndrome presenting with chronic inflammation of the joints. Patients with the same diagnosis can present with different phenotypes. In some patients severe joint inflammation and early joint destruction are observed, whereas a milder phenotype ...

Last Updated: 9 Jul 2017

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[Proteus mirabilis septic arthritis].
 

Author(s): Mohammed Sbiti, Bahia Bouhamidi, Lhoussaine Louzi

Journal:

 

Acute septic arthritis is rare. It is associated with poor prognosis in terms of mortality and morbidity. We report the case of a 61-year old patient with spontaneous Proteus mirabilis septic arthritis. He suffered from complicated diabetes associated with positive blood cultures ...

Last Updated: 4 Jul 2017

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Clinical Trial Information This information is provided by ClinicalTrials.gov

CPMC Early Undifferentiated Arthritis Registry
 

Status: Recruiting

Condition Summary: Arthritis

 

Last Updated: 31 Jan 2017

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Discovering the Antecedents of Rheumatoid Arthritis Flare
 

Status: Recruiting

Condition Summary: Rheumatoid Arthritis

 

Last Updated: 18 Oct 2017

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NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint
 

Status: Recruiting

Condition Summary: Knee Arthritis

 

Last Updated: 15 Nov 2016

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