[HTML][HTML] Targeted gold nanoparticles enable molecular CT imaging of cancer

…, NA Kotov, A Popovtzer, J Balter, TE Carey… - Nano …, 2008 - ncbi.nlm.nih.gov
Abstract X-ray based computed tomography (CT), is among the most convenient
imaging/diagnostic tools in hospitals today in terms of availability, efficiency and cost.
However, in contrast to magnetic resonance imaging (MRI) and various nuclear medicine

Cell surface antigens of human malignant melanoma: mixed hemadsorption assays for humoral immunity to cultured autologous melanoma cells

TE Carey, T Takahashi, LA Resnick… - Proceedings of the …, 1976 - National Acad Sciences
Abstract We studied how frequently patients with malignant melanoma have specific
antibody to cell surface antigens of cultured autologous melanoma cells as demonstrated by
mixed hemadsorption assays. Of 35 patients studied over periods ranging from 1 to 36

EGFR, p16, HPV Titer, Bcl-xL and p53, sex, and smoking as indicators of response to therapy and survival in oropharyngeal cancer

…, JA Bauer, CR Bradford, TE Carey - Journal of clinical …, 2008 - ascopubs.org
Purpose To prospectively identify markers of response to therapy and outcome in an organ-
sparing trial for advanced oropharyngeal cancer. Patients and Methods Pretreatment
biopsies were examined for expression of epidermal growth factor receptor (EGFR), p16, Bcl-

Chemoselection as a strategy for organ preservation in advanced oropharynx cancer: response and survival positively associated with HPV16 copy number

…, NE Wallace, CR Bradford, TE Carey - Journal of clinical …, 2008 - ascopubs.org
Purpose To test induction chemotherapy (IC) followed by concurrent chemoradiotherapy
(CRT) or surgery/radiotherapy (RT) for advanced oropharyngeal cancer and to assess the
effect of human papilloma virus (HPV) on response and outcome. Patients and Methods

Expression of N-cadherin by human squamous carcinoma cells induces a scattered fibroblastic phenotype with disrupted cell-cell adhesion.

S Islam, TE Carey, GT Wolf, MJ Wheelock… - The Journal of cell …, 1996 - jcb.rupress.org
E-cadherin is a transmembrane glycoprotein that mediates calcium-dependent, homotypic
cell-cell adhesion and plays an important role in maintaining the normal phenotype of
epithelial cells. Disruption of E-cadherin activity in epithelial cells correlates with formation of

Single‐marker identification of head and neck squamous cell carcinoma cancer stem cells with aldehyde dehydrogenase

MR Clay, M Tabor, JH Owen, TE Carey… - Head & …, 2010 - Wiley Online Library
Background In accord with the cancer stem cell (CSC) theory, only a small subset of cancer
cells are capable of forming tumors. We previously reported that CD44 isolates tumorigenic
cells from head and neck squamous cell cancer (HNSCC). Recent studies indicate that

[HTML][HTML] Landscape of genomic alterations in cervical carcinomas

…, CR Escareno, LA Akslen, TE Carey… - Nature, 2014 - ncbi.nlm.nih.gov
Abstract Cervical cancer is responsible for 10–15% of cancer-related deaths in women
worldwide 1, 2. The etiological role of infection with high-risk human papilloma viruses
(HPV) in cervical carcinomas is well established 3. Previous studies have implicated somatic

Recurrent cytogenetic abnormalities in squamous cell carcinomas of the head and neck region

…, SR Baker, GT Wolf, TE Carey… - Genes …, 1994 - Wiley Online Library
Abstract We characterized the breakpoints, gains, and losses of chromosome material in
squamous cell carcinomas of the head and neck region from 29 patients. Cell lines were
karyotyped in 1/3 of cases, direct preparations or early in vitro harvests in 1/3, and both in

Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974

…, ME McLaughlin, J Che, TE Carey… - Proceedings of the …, 2013 - National Acad Sciences
Abstract Wnt signaling is one of the key oncogenic pathways in multiple cancers, and
targeting this pathway is an attractive therapeutic approach. However, therapeutic success
has been limited because of the lack of therapeutic agents for targets in the Wnt pathway

Tobacco use in human papillomavirus–positive advanced oropharynx cancer patients related to increased risk of distant metastases and tumor recurrence

…, SJ Davis, PD Ward, CR Bradford, TE Carey - Clinical cancer …, 2010 - AACR
Purpose: The goal of this study was to examine the effect of tobacco use on disease
recurrence (local/regional recurrence, distant metastasis, or second primary) among patients
with human papillomavirus (HPV)–positive squamous cell carcinoma of the oropharynx