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Cleft Palate
 

Cleft Palate

Common Name(s)

Cleft Palate, Cleft palate, isolated

Cleft palate as an isolated malformation behaves as an entity distinct from cleft lip with or without cleft palate (see {119530}). Dominantly inherited cleft soft palate in 4 generations has been reported ({6:Jenkins and Stady, 1980}); see {119570}.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

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Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

Last Updated: 15 Apr 2013

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General Support Organizations

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Cleft Palate" for support, advocacy or research.

Logo
Oklahoma Family Network

To Provide emotional, informational and navigational support to those who have special health care needs or a disability, their families and the professionals who serve them. OFN promotes family/professional partnerships and family-centered care, assuring services are offered as recipients prefer..

http://www.oklahomafamilynetwork.org

Last Updated: 15 Apr 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Cleft Palate" returned 696 free, full-text research articles on human participants. First 3 results:

Nucleotide variants of the NAT2 and EGF61 genes in patients in Northern China with nonsyndromic cleft lip with or without cleft palate.
 

Author(s): Jiaqun Yan, Hongquan Song, Na Mi, Xiaohui Jiao, Yanru Hao

Journal: Medicine (Baltimore). 2017 Sep;96(37):e7973.

 

Non-syndromic cleft lip with or without cleft palate (NSCL/P) is a common orofacial congenital anomaly. The objective of the present study was to analyze the association of single nucleotide polymorphisms (SNPs) in the NAT2 and EGF61genes with NSCL/P in a Chinese population.

Last Updated: 14 Sep 2017

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Genome-wide analysis of parent-of-origin interaction effects with environmental exposure (PoOxE): An application to European and Asian cleft palate trios.
 

Author(s): Øystein A Haaland, Astanand Jugessur, Miriam Gjerdevik, Julia Romanowska, Min Shi, Terri H Beaty, Mary L Marazita, Jeffrey C Murray, Allen J Wilcox, Rolv T Lie, Håkon K Gjessing

Journal:

 

Cleft palate only is a common birth defect with high heritability. Only a small fraction of this heritability is explained by the genetic variants identified so far, underscoring the need to investigate other disease mechanisms, such as gene-environment (GxE) interactions and parent-of-origin ...

Last Updated: 12 Sep 2017

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BMP4 rs17563 polymorphism and nonsyndromic cleft lip with or without cleft palate: A meta-analysis.
 

Author(s): Yue-Hua Li, Jiaomei Yang, Ju-Lei Zhang, Jia-Qi Liu, Zhao Zheng, Da-Hai Hu

Journal: Medicine (Baltimore). 2017 Aug;96(31):e7676.

 

Previous studies have investigated the relationship between human bone morphogenetic protein 4 gene (BMP4) rs17563 polymorphism and nonsyndromic cleft lip with or without cleft palate (NSCL/P). However, the results remained inconsistent. Therefore, we conducted a meta-analysis to ...

Last Updated: 2 Aug 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Cleft Palate" returned 38 free, full-text review articles on human participants. First 3 results:

Treatment outcomes of pre-surgical infant orthopedics in patients with non-syndromic cleft lip and/or palate: A systematic review and meta-analysis of randomized controlled trials.
 

Author(s): Hamid Reza Hosseini, Eleftherios G Kaklamanos, Athanasios E Athanasiou

Journal:

 

Non-syndromic clefts lip and/or palate (CL/P) defects may have manifold significant and detrimental consequences for the affected individuals and their family environment. Although the use of pre-surgical infant orthopedics (PSIO) was introduced as a means to improve management and ...

Last Updated: 25 Jul 2017

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Predictive validity of the GOSLON Yardstick index in patients with unilateral cleft lip and palate: A systematic review.
 

Author(s): Cindy Buj-Acosta, Vanessa Paredes-Gallardo, José María Montiel-Company, Alberto Albaladejo, Carlos Bellot-Arcís

Journal:

 

Among the various indices developed for measuring the results of treatment in patients born with unilateral cleft lip and palate (UCLP), the GOSLON Yardstick index is the most widely used to assess the efficacy of treatment and treatment outcomes, which in UCLP cases are closely linked ...

Last Updated: 1 Jun 2017

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Association between IRF6 and 8q24 polymorphisms and nonsyndromic cleft lip with or without cleft palate: Systematic review and meta-analysis.
 

Author(s): Kachin Wattanawong, Sasivimol Rattanasiri, Mark McEvoy, John Attia, Ammarin Thakkinstian

Journal: Birth Defects Res. Part A Clin. Mol. Teratol.. 2016 Sep;106(9):773-88.

 

We conducted a systematic review and meta-analysis of interferon regulatory factor 6 and 8q24 polymorphisms with nonsyndromic cleft lip with/without cleft palate (NSCL/P).

Last Updated: 12 Sep 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Last Updated: 14 Dec 2016

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Dexmedetomidine vs Placebo for Pediatric Cleft Palate Repair
 

Status: Not yet recruiting

Condition Summary: Cleft Palate

 

Last Updated: 30 Jan 2017

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The Use of Fibrin Sealant to Reduce Post Operative Pain in Cleft Palate Surgery
 

Status: Recruiting

Condition Summary: Cleft Palate

 

Last Updated: 31 Oct 2016

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