[HTML][HTML] Guidelines for the use and interpretation of assays for monitoring autophagy

DJ Klionsky, K Abdelmohsen, A Abe, MJ Abedin… - Autophagy, 2016 - Taylor & Francis
Many researchers, especially those new to the field, need to determine which criteria are
essential for demonstrating autophagy, either for the purposes of their own research, or in
the capacity of a manuscript or grant review. 1 Acceptable standards are an important issue,

Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases

…, Y Zhang, J Chen, X Guo, Q Li, X Li, W Wang, Y Zhang… - Cell research, 2008 - nature.com
Abstract Dysregulated expression of microRNAs (miRNAs) in various tissues has been
associated with a variety of diseases, including cancers. Here we demonstrate that miRNAs
are present in the serum and plasma of humans and other animals such as mice, rats,

Synthesis and biological evaluation of the 1, 5-diarylpyrazole class of cyclooxygenase-2 inhibitors: identification of 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1 H …

…, K Seibert, AW Veenhuizen, YY Zhang… - Journal of medicinal …, 1997 - ACS Publications
A series of sulfonamide-containing 1, 5-diarylpyrazole derivatives were prepared and
evaluated for their ability to block cyclooxygenase-2 (COX-2) in vitro and in vivo. Extensive
structure− activity relationship (SAR) work was carried out within this series, and a number of

Pharmacological and biochemical demonstration of the role of cyclooxygenase 2 in inflammation and pain

K Seibert, Y Zhang, K Leahy… - Proceedings of the …, 1994 - National Acad Sciences
Abstract Nonsteroidal antiinflammatory drugs (NSAIDs) are widely used for the treatment of
inflammatory diseases, but significant side effects such as gastrointestinal erosion and renal
damage limit their use. NSAIDs inhibit the enzyme cyclooxygenase (COX), which catalyzes

Significant acidification in major Chinese croplands

…, XJ Liu, Y Zhang, JL Shen, WX Han, WF Zhang… - …, 2010 - science.sciencemag.org
Soil acidification is a major problem in soils of intensive Chinese agricultural systems. We
used two nationwide surveys, paired comparisons in numerous individual sites, and several
long-term monitoring-field data sets to evaluate changes in soil acidity. Soil pH declined

Geometric ad-hoc routing: Of theory and practice

F Kuhn, R Wattenhofer, Y Zhang… - Proceedings of the twenty …, 2003 - dl.acm.org
Abstract All too often a seemingly insurmountable divide between theory and practice can
be witnessed. In this paper we try to contribute to narrowing this gap in the field of ad-hoc
routing. In particular we consider two aspects: We propose a new geometric routing

[HTML][HTML] Fever with thrombocytopenia associated with a novel bunyavirus in China

…, SY Zhang, Y Liu, JD Li, YL Sun, L Zhang… - … England Journal of …, 2011 - Mass Medical Soc
Background Heightened surveillance of acute febrile illness in China since 2009 has led to
the identification of a severe fever with thrombocytopenia syndrome (SFTS) with an
unknown cause. Infection with Anaplasma phagocytophilum has been suggested as a

Pharmacological analysis of cyclooxygenase-1 in inflammation

CJ Smith, Y Zhang, CM Koboldt… - Proceedings of the …, 1998 - National Acad Sciences
Abstract The enzymes cyclooxygenase-1 and cyclooxygenase-2 (COX-1 and COX-2)
catalyze the conversion of arachidonic acid to prostaglandin (PG) H 2, the precursor of PGs
and thromboxane. These lipid mediators play important roles in inflammation and pain and

Tissue Doppler imaging is superior to strain rate imaging and postsystolic shortening on the prediction of reverse remodeling in both ischemic and nonischemic heart …

CM Yu, JWH Fung, Q Zhang, CK Chan, YS Chan… - Circulation, 2004 - Am Heart Assoc
Background—A number of noninvasive techniques have been used to predict the
effectiveness of cardiac resynchronization therapy (CRT) in heart failure patients, in
particular left ventricular (LV) reverse remodeling. This study compared the relative

Symbiotic gut microbes modulate human metabolic phenotypes

…, Y Zhang, J Shen, X Pang, M Zhang… - Proceedings of the …, 2008 - National Acad Sciences
Abstract Humans have evolved intimate symbiotic relationships with a consortium of gut
microbes (microbiome) and individual variations in the microbiome influence host health,
may be implicated in disease etiology, and affect drug metabolism, toxicity, and efficacy.