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Diabetes mellitus type 1
 

Diabetes mellitus type 1

Common Name(s)

Diabetes mellitus type 1

Diabetes mellitus type 1 (DM1) is a condition in which cells in the pancreas (beta cells) stop producing insulin, causing abnormally high blood sugar levels. Lack of insulin results in the inability of the body to use glucose for energy and control the amount of sugar in the blood. DM1 can occur at any age, but usually develops by early adulthood, most often in adolescence. Symptoms of high blood sugar may include frequent urination, excessive thirst, fatigue, blurred vision, tingling or loss of feeling in the hands and feet, and weight loss. The exact cause of DM1 is unknown, but having certain "variants" of specific genes may increase a person's risk to develop the condition. A predisposition to develop DM1 runs in families, but no known inheritance pattern exists. Treatment includes blood sugar control and insulin replacement therapy. Improper control can cause recurrence of high blood sugar, or abnormally low blood sugar (hypoglycemia) during exercise or when eating is delayed. If not treated, the condition can be life-threatening. Over many years, chronic high blood sugar may be associated with a variety of complications that affect many parts of the body.
 

Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 1" for support, advocacy or research.

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Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

Last Updated: 6 Mar 2013

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Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

Last Updated: 28 Mar 2013

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General Support Organizations

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How do you compare to others with this condition?

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Advocacy and Support Organizations

 

Condition Specific Organizations

Following organizations serve the condition "Diabetes mellitus type 1" for support, advocacy or research.

Logo
Diabetes Hands Foundation

We work to connect, engage, and empower people touched by diabetes while keeping in mind a vision of a world where people with diabetes and their loved ones do not feel alone, understand and manage a life with diabetes and work together towards a better future.

http://www.diabeteshandsfoundation.org

Last Updated: 6 Mar 2013

View Details
Logo
Taking Control of Your Diabetes

Guided by the belief that every person with diabetes has the right to live a healthy, happy, and productive life, Taking Control of Your Diabetes educates and motivates people with diabetes to take a more active role in their condition and provides innovative and integrative continuing diabetes education to medical professionals caring for people with diabetes.

http://www.tcoyd.org

Last Updated: 28 Mar 2013

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General Support Organizations

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Scientific Literature

Articles from the PubMed Database

Research articles describe the outcome of a single study. They are the published results of original research.
The terms "Diabetes mellitus type 1" returned 815 free, full-text research articles on human participants. First 3 results:

Phase separation of the plasma membrane in human red blood cells as a potential tool for diagnosis and progression monitoring of type 1 diabetes mellitus.
 

Author(s): Giuseppe Maulucci, Ermanno Cordelli, Alessandro Rizzi, Francesca De Leva, Massimiliano Papi, Gabriele Ciasca, Daniela Samengo, Giovambattista Pani, Dario Pitocco, Paolo Soda, Giovanni Ghirlanda, Giulio Iannello, Marco De Spirito

Journal:

 

Glycosylation, oxidation and other post-translational modifications of membrane and transmembrane proteins can alter lipid density, packing and interactions, and are considered an important factor that affects fluidity variation in membranes. Red blood cells (RBC) membrane physical ...

Last Updated: 7 Sep 2017

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Prediction of glycaemic control in young children and adolescents with type 1 diabetes mellitus using mixed-effects logistic regression modelling.
 

Author(s): Michiel Joost van Esdonk, Bonnie Tai, Andrew Cotterill, Bruce Charles, Stefanie Hennig

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Glycaemic control in children and adolescents with type 1 diabetes mellitus can be challenging, complex and influenced by many factors. This study aimed to identify patient characteristics that were predictive of satisfactory glycaemic control in the paediatric population using a ...

Last Updated: 2 Aug 2017

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Plasma bradykinin and early diabetic nephropathy lesions in type 1 diabetes mellitus.
 

Author(s): Kevin M Wheelock, Jian Cai, Helen C Looker, Michael L Merchant, Robert G Nelson, Gudeta D Fufaa, E Jennifer Weil, Harold I Feldman, Ramachandran S Vasan, Paul L Kimmel, Brad H Rovin, Michael Mauer, Jon B Klein,

Journal:

 

To examine the association of bradykinin and related peptides with the development of diabetic nephropathy lesions in 243 participants with type 1 diabetes (T1D) from the Renin-Angiotensin System Study who, at baseline, were normoalbuminuric, normotensive and had normal or increased ...

Last Updated: 12 Jul 2017

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Reviews from the PubMed Database

Review articles summarize what is currently known about a disease. They discuss research previously published by others.
The terms "Diabetes mellitus type 1" returned 103 free, full-text review articles on human participants. First 3 results:

The change of serum tumor necrosis factor alpha in patients with type 1 diabetes mellitus: A systematic review and meta-analysis.
 

Author(s): Yong-Chao Qiao, Yin-Ling Chen, Yan-Hong Pan, Fang Tian, Yan Xu, Xiao-Xi Zhang, Hai-Lu Zhao

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The aim of this study was used meta-analysis to investigate changes of serum tumor necrosis factor-alpha (TNF-α) in patients with type 1 diabetes mellitus (T1DM).

Last Updated: 20 Apr 2017

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An association of type 1 diabetes mellitus with auditory dysfunction: A systematic review and meta-analysis.
 

Author(s): Zhi-Pan Teng, Rui Tian, Fen-Li Xing, Hui Tang, Jin-Jing Xu, Bing-Wen Zhang, Jian-Wei Qi

Journal: Laryngoscope. 2017 Jul;127(7):1689-1697.

 

To establish the relationship between the presence of type 1 diabetes mellitus (DM) and auditory dysfunction in clinical settings by a systematic review and meta-analysis of currently available published data.

Last Updated: 7 Oct 2016

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Effect of Associated Autoimmune Diseases on Type 1 Diabetes Mellitus Incidence and Metabolic Control in Children and Adolescents.
 

Author(s): Aleksandra Krzewska, Iwona Ben-Skowronek

Journal: Biomed Res Int. 2016 ;2016():6219730.

 

Type 1 diabetes mellitus (T1DM) is one of the most common chronic diseases developing in childhood. The incidence of the disease in children increases for unknown reasons at a rate from 3 to 5% every year worldwide. The background of T1DM is associated with the autoimmune process ...

Last Updated: 15 Aug 2016

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Clinical Trial Information This information is provided by ClinicalTrials.gov

Use of Stem Cells in Diabetes Mellitus Type 1
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 3 May 2017

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Clinical Trial Assessing the GNbAC1 in Patients With Onset of Type 1 Diabetes Within 4 Years
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 19 Sep 2017

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A Pilot Study of the Therapeutic Potential of Stem Cell Educator Therapy in Type 1 Diabetes
 

Status: Recruiting

Condition Summary: Diabetes Mellitus Type 1

 

Last Updated: 17 Jul 2017

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