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 ResearchCenters and FacilitiesPeriodontal Research Center     April 17, 2014  

 

 

Periodontal Disease Clinical Research Center

Contacts:

Director
 
Associate Director

The Periodontal Research Center at Buffalo is funded by the National Institutes of Health [NIH] as one of their specialized clinical research centers for the study of periodontal disease. The center has enjoyed continuous support since 1977, initially from the National Institute for Dental and Craniofacial Research [NIDCR], and more recently from a combination of NIH and industrial support.

Past studies have focused on etiology and host response in periodontal disease and have led to the development of concepts and regimes for anti-infective therapy. Next, the UB researchers began epidemiological studies to identify risk factors for periodontal disease. To date, diabetes, smoking, the presence of periodontal pathogens, stress, distress, and coping measures have been identified as potential risk factors for periodontal disease. Future studies include a continuation of studies of putative risk factors, including longitudinal incidence studies to firmly establish risk factors. The center will also carry out intervention studies directed at modulating risk factors for better management of periodontal disease risk populations.

Several new areas of research have been added:
 

  • Studies of the association of periodontal disease with systemic diseases, including diabetes, cardiovascular disease, stroke, osteoporosis, and respiratory infection
  • Studies of the use of growth factors including PDGF and bFGF to regenerate periodontal ligament, cementum, and bone around periodontally diseased teeth, and to regenerate bone around implants and in surgical defects
  • Genome-wide association studies of periodontal disease
  • Studies of salivary and serum biomarkers of disease

The Periodontal Research Center's full-time staff provides opportunities for dental and medical students, graduate students, and visiting scientists to participate in clinically oriented research projects. The center also serves as a regional center for multicenter randomized clinical trials to test periodontal therapies, diagnostics, and etiopathologic mechanisms.

RESEARCH >

For nearly five decades, the School of Dental Medicine has been a national leader in the science behind oral health.
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RESEARCH >

In addition to steady activity in our laboratories and clinics, students and faculty are preparing and submitting abstracts for the annual meeting of the International Association for Dental Research.
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The complete classroom-to-clinic experience provided by Oral Diagnostic Sciences supported by several specialty care clinics including one associated with the Center for Orofacial Pain Research.
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EDUCATION >

  

Established in 1892, the School of Dental Medicine continues to educate general practitioners, specialists and biomedical scientists in the art and science of oral health through our comprehensive accredited programs.

EDUCATION >

The tradition of practicing dentists taking time to teach is as old as dentistry itself; the central role of practitioners as faculty is as old as the earliest organized dental schools.

EDUCATION >

As a proud member of the prestigious Association of American Universities (AAU), the University at Buffalo is committed to discovery, both basic and applied research, development and scholarship particularly related to oral health and disease.

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