Chunhao Li 

Department of Oral Biology

Associate Professor

Specialty/Research Focus

Microbiology; Oral Biology

Faculty Research Profile

 
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Education and Training:
  • Postdoctoral Fellow, West Virginia University (2002)
  • MS, Chinese Academy of Preventive Medicine (1996)
  • MD, Anhui Medical University (1990)
Employment:
  • Associate Professor, Oral Biology, SUNY at Buffalo (2011-present)
  • Assistant Professor, Oral Biology, State University of New York at Buffalo (2006-2011)
  • Research Assistant Professor, Dept. of Microbiology, Immunology & Cell Biology, West Virginia University (2003-2005)
  • Research Instructor, Microbiology, Immunology and Cell Biology, West Virginia University (2002-2003)
  • Post Doctoral Fellow, Microbiology and Immunology, West Virginia University (1997-2002)

Research Expertise:
  • Bacterial genetics and Pathogenesis: My research is trying to understand the biology, genetics and pathogenesis of pathogenic spirochetes, including Borrelia burgdorferi (Lyme disease), oral Treponema denticola (periodontal infections), and Brachyspira species (swine dysentery and human diarrheal disease).
  • Oral Microbiology and Periodontal disease
Grants and Sponsored Research:
  • August 2013-July 2018
    PROTEIN-PROTEIN COVALENT BONDING AND TREPONEMA MOTILITY
    NDCR, NIH
    Role: Co-Investigator
  • July 2013-June 2018
    Exploring New Virulence factors of the Oral Spirochete Treponema denticola
    NIDCR, NIH
    Role: Principal Investigator
  • April 2012-March 2017
    Amylase Binding and Gene Expression in S. gordonii.
    NIH-NIDCR
    Role: Co-Investigator
  • July 2010-June 2014
    Developing Inhibitors of LuxS-Dependent Quorum Sensing Systems in Oral Bacteria
    NIDCR, NIH
    Role: Principal Investigator
  • September 2008-August 2013
    Understanding Unique Aspects of Motility and Chemotaxis in Borrelia burgdorferi
    NIAID, NIH
    Role: Principal Investigator
  • September 2008-August 2011
    Regulation of Host-adaptation of the Lyme disease Spirochete Borrelia burgdorferi
    NIAID, NIH
    Role: Principal Investigator
  • August 2008-July 2011
    Role of Zonula Occludens Toxin in the Pathogenesis of Treponema denticola
    NIDCR, NIH
    Role: Principal Investigator
  • July 2007-June 2011
    Role of Motility and Chemotaxis in the Pathogenesis of Lyme disease Spirochete Borrelia burgdorferi
    American Heart Association
    Role: Principal Investigator
  • April 2004-March 2007
    Role of Motility in Borrelia burgdorferi Pathogenesis
    NIAMS, NIH
    Role: Principal Investigator

Journal Articles:
See All (33 Total) >

Books and Book Chapters:
  • Goldstein SF, Li C, Liu J, Miller M, Motaleb MA, Norris SJ, Silversmith RE, Wolgemuth CW, Charon NW. The Chic Motility and Chemotaxis of Borrelia burgdorferi.. 2010.
  • Li C. Bacterial Cell Structure. 2009.
  • Charon NW, Li C, Goldstein SF. The Beguiling Motility of the Genus Treponema. Treponema Molecular and Cellular Biology. 2006.
  • Li C, Motaleb MA, Sal M, Goldstein SF, Charon NW. Gyration, Rotation, Periplasmic Flagella: The Biology of Spirochetes Motility.. Cellular and Molecular Biology of Spirochetes. 2001.
Professional Memberships:
  • Member, American Society of Microbiology (1998)
Presentations:
  • The response regulator Rrp1 regulates chitobiose utilization and virulence of the Lyme disease spirochete Borrelia burgdorferi, BLAST XII, Bacterial locomotion and Signal transduction, Inc. (2013)
  • Exploring the roles of neuraminidases in periodontal pathogens, Seminar series, University of Louisville (2012)
  • Roles of neuraminidases in periodontal pathogens, Seminar series, West Virginia University (2012)
  • Developing a modified gentamycin antibiotic resistance maker for the targeted mutagenesis of Treponema denticola, Rochester Conference on Oral Biology, University of Rochester (2011)
  • A neuraminidase contributes to the biofilm formation, motility and virulence of oral Treponema denticola, Rochester Conference on Oral Biology, Rochester University (2011)
  • Sialylation, Biofilm Formation & Virulence of Porphyromonas gingivalis, International Symposium of Microbial Biofilm, Johnson and Johnson, West China University (2011)
  • Carbon storage regulator A (CsrABb) is a repressor of Borrelia burgdorferi flagellin protein FlaB, BLAST XI, Bacterial locomotion and Signal transduction, Inc (2011)
  • Exploring new virulence factors in the oral spirochete Treponema denticola, Invited speaker, University of Florida at Gainesville (2010)
  • CsrA (Bb0184) represses the motility and chemotaxis of Borrelia burgdorferi, Gordon Conferences (2010)
  • The Lyme disease spirochete Borrelia burgdorferi FlgJ controls flagellar hook orientation, Gordon Conferences (2010)
  • Role of Mac-like protein in the pathogenesis of oral spirochete T. denticola, Gordon Conference (2010)
  • CsrA (Bb0184) represses the motility and chemotaxis of Borrelia burgdorferi, Gordon Conference (2010)
  • Localization of chemotaxis complex in the Lyme disease spirochete Borrelia burgdorferi, Gordon Conference (2010)
  • Chunhao Li. Identification of a Mac-like virulence factor in oral Treponema denticola, IADR/AADR/CADR (2009)
  • Identification of a Mac-like virulence factor in oral Treponema denticola, Research Conferences, SUNY at Buffalo (2009)
  • Training on Anaerobes (2008)
  • A putative motor switch complex protein FliG-1 is essential for the motility and virulence of Borrelia burgdorferi., Gordon Conference, Biology of Spirochetes (2008)
  • A putative motor switch complex protein FliG-1 is essential for the motility and virulence of Borrelia burgdorferi, Gordon Conference (2008)
  • Transcription and genetic analyses of an N-acetylmuramyl-L-alanine amidase (amiA) homolog in Borrelia burgdorferi, Gordon Conferences (2008)
  • Transcription and genetic analyses of an N-acetylmuramyl-L-alanine amidase (amiA) homolog in Borrelia burgdorferi, Gordon Conference (2008)
  • Invited as Speaker, Bacterial Locomotion and Signal Transduction, BLAST IX (2006)
  • Invited Speaker, Bacterial Locomotion and Signal Transduction, BLAST VI, Bacterial Locomotion and Signal Transduction, BLAST VI (2000)
  • Invited Speaker, Bacterial Locomotion and Signal Transduction, BLAST V (1999)
  • Invited Lecturer and Laboratory Instructor, World Health Organization (1996)
See All (24 Total) >
Service Activities:
  • Faculty Senate Executive Committee; Member (2010)
  • School of Dental Medicine Graduate Committee, Admissions, Oral Biology; Member (2009)
  • School of Dental Medicine Graduate Committee, Recruiting, Oral Biology; Member (2008)
  • School of Dental Medicine Student Research and Honors Committee; Member (2007)
  • School of Dental Medicine Infection Control/Biohazard Committee; Member (2006)
  • School of Dental Medicine Thesis Advisory Committee; Member (2006)
  • School of Dental Medicine Graduate Committee, Preliminary Exams, Oral Biology; Member (2006)

  • PhD thesis committee; Committee Member (2012)
  • Oral Biology faculty search committee; Committee Member (2012-2013)
  • Graduate program committee; Committee Member (2011)
  • Buffalo Chinese School; Secretary (2010-2012)
  • the MRBSB Faculty Advisory Committee; Molecular Recognition in Biological Systems and Bioinformatics' (MRBSB) focus centers on research done on every level of a given biological system, whether it is chemical, molecular, genetic, cellular, tissue, organ or whole organ systems. Bringing together researchers from the School of Medicine and Biomedical Sciences; the School of Engineering and Applied Sciences; the New York State Center of Excellence in Bioinformatics and Life Sciences; Roswell Park Cancer Institute and several departments within the College of Arts and Sciences, MRBSB looks at biological systems at the cross-section between chemistry and biology. ; Committee Member (2010)
  • Dental School Dean Search Committee; Recruiting new dean of Dental School of Medicine, SUNY at Buffalo; Committee Member (2009-2009)
  • IGPBS Admissions Committee; Committee Member (2008-2011)
  • Student Research & Honors Committee; Committee Member (2007)
  • Oral Biology Seminars Committee; Chair (2006-2009)
  • Faculty Search Committee, Dept. of Oral Biology; Recruiting new faculty members, the Department of Oral Biology, SUNY at Buffalo; Committee Member (2006-2007)
  • Infection and Biohazard Control Committee; Committee Member (2006-2009)
See All (18 Total) >

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Contact Information

304B Foster Hall
Oral Biology
3435 Main St.
Buffalo, NY 14214-8031
Phone: 716-829-6014
Fax: 716-829-3942
Email: cli9@buffalo.edu


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